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Keywords: Phrenic neuron
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Journal Articles
Carolina Barcellos Machado, Kevin C. Kanning, Patricia Kreis, Danielle Stevenson, Martin Crossley, Magdalena Nowak, Michelina Iacovino, Michael Kyba, David Chambers, Eric Blanc, Ivo Lieberam
Journal:
Development
Development (2014) 141 (4): 784–794.
Published: 15 February 2014
... is known about how this crucial subtype of motor neuron is generated during embryogenesis. Here, we used direct differentiation of motor neurons from mouse embryonic stem cells as a tool to identify genes that direct phrenic neuron identity. We find that three determinants, Pou3f1, Hoxa5 and Notch, act...
Includes: Supplementary data
