... 2000 C. elegans Homeobox gene Axonal guidance Phox2 The development of the nervous system involves the navigation of axons towards their synaptic targets along complex and precise pathways. This navigation is directed by responses to repulsive and attractive cues ( Tessier-Lavigne...

... cells first express the bHLH transcriptional regulator Cash-1 (a chicken achaete-scute homologue), followed by coordinate expression of Phox2, a paired homeodomain protein, and GATA-2, a zinc finger protein. SCG10, a pan-neuronal membrane protein, is first detected one stage later, followed...