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Keywords: Phosphatidylinositol 4-phosphate
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Journal Articles
Lauren M. Del Bel, Nigel Griffiths, Ronit Wilk, Ho-Chun Wei, Anastasia Blagoveshchenskaya, Jason Burgess, Gordon Polevoy, James V. Price, Peter Mayinger, Julie A. Brill
Journal:
Development
Development (2018) 145 (11): dev151571.
Published: 31 May 2018
... that resemble rst mutants. S ac1 ts retinas exhibit elevated levels of phosphatidylinositol 4-phosphate (PI4P), consistent with the role of Sac1 as a PI4P phosphatase. Indeed, genetic rescue and interaction experiments reveal that restriction of PI4P levels by Sac1 is crucial for normal eye development. Rst...
Includes: Supplementary data
