...Aihua Mao; Mingming Zhang; Linwei Li; Jie Liu; Guozhu Ning; Yu Cao; Qiang Wang ABSTRACT The paired pharyngeal arch arteries (PAAs) are transient blood vessels connecting the heart with the dorsal aorta during embryogenesis. Although PAA malformations often occur along with pharyngeal pouch defects...

...Kazunori Okada; Shinji Takada ABSTRACT Pharyngeal arches (PAs) are segmented by endodermal outpocketings called pharyngeal pouches (PPs). Anterior and posterior PAs appear to be generated by different mechanisms, but it is unclear how the anterior and posterior PAs combine. Here, we addressed...

... is segmented by the reiterative formation of endodermal outpocketings called pharyngeal pouches, the molecular network underlying the reiterative pattern remains unclear. Here, we show that pax1 plays crucial roles in pouch segmentation in medaka ( Oryzias latipes ) embryos. Importantly, pax1 expression...

...Jennifer R. Gardiner; Abigail L. Jackson; Julie Gordon; Heiko Lickert; Nancy R. Manley; M. Albert Basson The thymus and parathyroid glands are derived from the third pharyngeal pouch endoderm. The mechanisms that establish distinct molecular domains in the third pouch and control the subsequent...

..., is aberrant in that it invades the otic placode territory. foo is expressed in pharyngeal pouch endoderm and is required for pouch expression of pax8 and proper patterning of other markers in the pouch such as nkx2.3 . In foo/foo embryos, we observed a failure to maintain fgf3 expression in the pouches...