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Keywords: Pharyngeal arch artery
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Journal Articles
Journal: Development
Development (2003) 130 (25): 6361–6374.
Published: 22 December 2003
... ablation of Fgf8 gene function in the pharyngeal arch ectoderm and endoderm. Remarkably, ablating FGF8 protein in the pharyngeal arch ectoderm causes failure of formation of the fourth pharyngeal arch artery that results in aortic arch and subclavian artery anomalies in 95% of mutants; these defects...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4591–4603.
Published: 01 October 2002
... for FGF8 during development of pharyngeal arch, pharyngeal pouch and neural crest-derived tissues. We show that FGF8 deficient embryos have lethal malformations of the cardiac outflow tract, great vessels and heart due, at least in part, to failure to form the fourth pharyngeal arch arteries, altered...