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Keywords: Permeability barrier
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Journal Articles
Journal: Development
Development (2020) 147 (20): dev192997.
Published: 16 October 2020
... with unclear mechanisms. Here, we analyzed Caenorhabditis elegans mutants deleted of the sole SEIPIN gene, seip-1 . Homozygous seip-1 mutants displayed penetrant embryonic lethality, which is caused by the disruption of the lipid-rich permeability barrier, the innermost layer of the C. elegans embryonic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (12): 2767–2777.
Published: 15 June 2003
...Jean Jaubert; Jun Cheng; Julia A. Segre Dysfunction of the epidermal permeability barrier can result in dehydration, electrolyte imbalance and poor thermoregulation. Immature skin is a portal of entry for infectious agents and potential toxins in topically applied substances. As the skin is one...
Journal Articles
Journal: Development
Development (2002) 129 (7): 1775–1784.
Published: 01 April 2002
...Kursad Turksen; Tammy-Claire Troy A defective epidermal permeability barrier (EPB) in premature birth remains a leading cause of neonatal death as a result of its associated complications, which include poor temperature stability, infection by micro-organisms through the skin, and the outflow...