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Keywords: Pericytes
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Reproductive biology
Journal: Development
Development (2019) 146 (4): dev174037.
Published: 22 February 2019
... system. These phenotypes arise from abnormal gene expression patterns that reflect defective kinase signaling, including TGFβ and several receptor tyrosine kinase pathways. USP22 deletion in endothelial cells and pericytes that are induced from embryonic stem cells also hinders these signaling cascades...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev165589.
Published: 25 January 2019
... of expression of abcc9 , a pericyte marker in adult mice and zebrafish, occurs almost coincidentally with an increment in pdgfrb expression in peri-arterial mesenchymal cells, suggesting that these transcriptional changes mark the specification of MC lineage cells from naïve pdgfrb low mesenchymal cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1328–1339.
Published: 15 April 2016
...Koji Ando; Shigetomo Fukuhara; Nanae Izumi; Hiroyuki Nakajima; Hajime Fukui; Robert N. Kelsh; Naoki Mochizuki Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the endothelial cells (ECs) to regulate vascular stability and homeostasis. Here, we clarified the mechanism...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1242–1253.
Published: 01 April 2015
... observed that 90% of capillaries were associated with pericytes in adult mouse and human muscle. During post-natal growth, newly formed vessels with their neuroglial 2 proteoglycan (NG2)-positive pericytes became progressively associated with the post-natal muscle stem cells, as myofibers increased in size...
Journal Articles
Journal: Development
Development (2014) 141 (2): 307–317.
Published: 15 January 2014
...Yuying Wang; Luyuan Pan; Cecilia B. Moens; Bruce Appel Brain pericytes are important regulators of brain vascular integrity, permeability and blood flow. Deficiencies of brain pericytes are associated with neonatal intracranial hemorrhage in human fetuses, as well as stroke and neurodegeneration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (11): 2657–2668.
Published: 01 June 2005
...-embryonic tissues and in angioblast progenitors forming the primary vascular plexus. Later, expression is highly restricted to perivascular cells in most blood vessels resembling pericytes or vascular smooth muscle cells. Viable Anxa5 - lacZ + perivascular cells were isolated from embryos as well as adult...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1847–1857.
Published: 15 April 2004
... importance of different cellular sources of PDGFB has not been established. Using Cre-lox techniques, we show here that genetic ablation of Pdgfb in endothelial cells leads to impaired recruitment of pericytes to blood vessels. The endothelium-restricted Pdgfb knockout mutants also developed organ defects...