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Keywords: Pectoral fin
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Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (4): 753–762.
Published: 15 February 2015
... understood. Here, we show that in zebrafish the transcription factor foxc1a is dispensable for trunk motor nerve guidance but is required to guide spinal nerves innervating the pectoral fins, equivalent to the tetrapod forelimbs. In foxc1a null mutants, instead of converging with other nerves at the plexus...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (22): 5161–5170.
Published: 15 November 2002
... phenotype ( Fig. 1A,C ),injection of a tbx5 morpholino gave a range of altered fin phenotypes depending on the amount injected. With the highest non-toxic levels of injected morpholino (10 ng), the most common phenotype was complete loss of pectoral fins (95%, n =250; Table 1 ; Fig. 1B ). Cartilage...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4635–4645.
Published: 1 October 2002
... transcription factors that play important roles in cell-type specification and morphogenesis. In a screen for mutations affecting zebrafish cardiac function, we isolated the recessive lethal mutant heartstrings , which lacks pectoral fins and exhibits severe cardiac dysfunction, beginning with a slow heart rate...
Journal Articles
Journal: Development
Development (2000) 127 (19): 4169–4178.
Published: 1 October 2000
... pectoral fin bud to maintain signaling from the apical fold, which is homologous to the AER of tetrapods. dak acts synergistically with Shh to induce fgf4 and fgf8 expression but independently of Shh in promoting apical fold morphogenesis. The failure of dak mutant fin buds to progress from the initial fin...