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Keywords: Pbx
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
... recent advances in determining MEIS function and discusses new insights into their role in the pathogenesis of solid cancers. Cell cycle Embryogenesis Epigenetic modification of chromatin MEIS PBX Post-transcriptional and posttranslational control Solid cancer Ever since their...
Journal Articles
Journal: Development
Development (2019) 146 (14): dev167882.
Published: 26 July 2019
... involving global and regional genetic regulation. Cartilage Patterning Morphology Superstructure Sox9 Scleraxis Modularity Gli3 Pbx Hox Mouse In addition to these genes, our transcriptomic analysis identified 12 more candidate genes that were reportedly involved in long bone...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 719–729.
Published: 15 February 2013
..., dorsal-ventral and medial-lateral axes. Wnt and several Hox genes are expressed at the posterior pole, whereas Wnt inhibitory genes, Fgf inhibitory genes, and prep , which encodes a TALE-family homeodomain protein, are expressed at the anterior pole. We found that Smed-pbx ( pbx for short), which encodes...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (15): 2559–2569.
Published: 01 August 2010
... controlling limb morphogenesis have limited influence on scapula formation. Analysis of mouse mutants for Pbx and Emx2 genes has suggested their potential roles in girdle development. In this study, by generating compound mutant mice, we examined the genetic control of scapula development by Pbx genes and...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3577–3586.
Published: 01 November 2008
... contribution to distinct regulatory pathways in cardiovascular development. † Authors for correspondence (e-mails: chingpin@stanford.edu ; mcleary@stanford.edu ) * These authors contributed equally to this work 8 9 2008 © 2008. 2008 Pbx Hox Pax3 Msx2 Heart development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3371–3382.
Published: 15 September 2007
... myogenic program is modulated to achieve muscle fiber-type-specific gene expression. Pbx homeodomain proteins mark promoters of a subset of Myod target genes,including myogenin ( Myog ); thus, Pbx proteins might modulate the program of myogenesis driven by Myod. By inhibiting Pbx function in zebrafish...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (3): 613–627.
Published: 01 February 2004
...Gianluca Deflorian; Natascia Tiso; Elisabetta Ferretti; Dirk Meyer; Francesco Blasi; Marino Bortolussi; Francesco Argenton In this study we analysed the function of the Meinox gene prep1.1 during zebrafish development. Meinox proteins form heterotrimeric complexes with Hox and Pbx members...
Journal Articles
Journal: Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
... proteins to a larger family of non-Hox homeodomain proteins. * Author for correspondence (e-mail: Jim.Jaynes@mail.tju.edu ) 7 11 2002 © 2003. 2003 Drosophila Embryogenesis Homeodomain Transcription Repressor Cofactor Pbx Meis The engrailed ( en ) gene is a...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 01 October 2002
... homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud. Dev. Dyn . 214 , 66 -80. Chang, C. P., Shen, W. F., Rozenfeld, S., Lawrence, H. J., Largman, C. and Cleary, M. L. ( 1995 ). Pbx proteins display hexapeptide-dependent...
Journal Articles
Journal: Development
Development (2002) 129 (3): 585–595.
Published: 01 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4139–4151.
Published: 01 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3595–3607.
Published: 15 September 2001
... Hoxa3 expression through a conserved auto/cross-regulatory loop. This block of similarity is also present in the human and horn shark loci, and contains two bipartite Hox/Pbx-binding sites that are necessary for its in vivo activity in the hindbrain. These HOX/PBC sites are positioned near a conserved...