...-38 and pax-2 ) influence both somatic and germline cell death in C. elegans . Using genetic and molecular experiments, we show that the Pax proteins act as transcriptional regulators of ced-9 , the C. elegans bcl-2 gene. These results identify a mechanism for Pax2/5/8-mediated regulation of cell...

... (e-mail: [email protected] ) 19 03 1996 © 1996 by Company of Biologists 1996 forebrain midbrain hindbrain rhombomeres dorsoventral patterning cyclops axial pax-2 hlx-1 The establishment of the dorsoventral axis of the neural plate is one...

... embryo. The former give rise to the genital tracts, ureters and kidney collecting duct system, whereas mesenchymal components undergo epithelial transformation to form nephrons in both the mesonephric (embryonic) and metanephric (definitive) kidney. Pax-2 is a transcriptional regulator of the paired-box...

...Gabriella Ryan; Victoria Steele-Perkins; Jennifer F. Morris; Frank J. Rauscher, III; Gregory R. Dressler ABSTRACT The developmental, regulatory gene Pax-2 is activated during early kidney morphogenesis and repressed in mature renal epithelium. Persistent Pax-2 expression is also observed...

...Uwe W. Rothenpieler; Gregory R. Dressler ABSTRACT The conversion of mesenchyme to epithelium during the embryonic development of the mammalian kidney requires reciprocal inductive interactions between the ureter and the responding metanephric mesenchyme. The Pax-2 gene is activated...