1-3 of 3
Keywords: Patched 1
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2010) 137 (1): 133–140.
Published: 01 January 2010
... of Shh. However, as the Ptch1 −/− cells have a constitutively activated Shh response, we cannot test the signaling range of Shh in Ptch1 −/− tissue. * Author for correspondence ( roelink@berkeley.edu ) 31 10 2009 © 2010. 2010 Dispatched 1 Patched 1 Sonic hedgehog...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3515–3524.
Published: 15 October 2009
...Natalie C. Butterfield; Vicki Metzis; Edwina McGlinn; Stephen J. Bruce; Brandon J. Wainwright; Carol Wicking The vertebrate hedgehog receptor patched 1 (Ptc1) is crucial for negative regulation of the sonic hedgehog (Shh) pathway during anterior-posterior patterning of the limb. We have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1947–1956.
Published: 01 June 2008
... Ihh in the cartilage of PTHrP -/- embryos or inactivating patched 1( Ptch1 ), a negative regulator of hedgehog (Hh) signaling, accelerated chondrocyte hypertrophy in the PTHrP -/- embryos. Conversely, when Hh signaling was blocked by cyclopamine or by removing Smoothened ( Smo ), a positive regulator...
Includes: Supplementary data