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Keywords: Paraxial mesoderm
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Journal Articles
Journal: Development
Development (2020) 147 (10): dev183996.
Published: 26 May 2020
... deletions, reveal that Shh that transits through the sclerotome is presented to the neuroepithelium from its basal aspect to affect motoneuron development. BMP Dermomyotome Dorso-ventral patterning Hb9 Motoneurons Myotome Neural tube Nkx Paraxial mesoderm Olig2 Pax7 Retinoic acid Somite...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (16): dev165431.
Published: 23 August 2018
.... Differentiation Disease modeling Fibrodysplasia ossificans progressiva Induced pluripotent stem cells Paraxial mesoderm Recapitulation of endogenous signaling environments is considered to be key for the induction of desired cell types from pluripotent stem cells (PSCs). Developmental biology studies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (6): dev157339.
Published: 19 March 2018
... Body skeletal muscles derive from the paraxial mesoderm, which forms in the posterior region of the embryo. Using microarrays, we characterize novel mouse presomitic mesoderm (PSM) markers and show that, unlike the abrupt transcriptome reorganization of the PSM, neural tube differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3808–3818.
Published: 15 October 2017
... lateral plate differentiation is profoundly altered. During this period, global mRNA levels are unchanged in the PSM, with only a minor subset of genes dysregulated. Together, our data strongly suggest that the TAF10-containing canonical TFIID and SAGA complexes are dispensable for early paraxial mesoderm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (12): 2104–2122.
Published: 15 June 2017
... of Biologists Ltd 2017 Summary: This Review discusses the mechanisms that underpin the formation of skeletal muscle during development and its recapitulation from pluripotent stem cells in vitro . Skeletal myogenesis Muscle differentiation Paraxial mesoderm Somite Dermomyotome Muscular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 664–676.
Published: 15 February 2017
... endocytosis pathway ( Delva and Kowalczyk, 2009 ), this led us to ask whether PAPC regulates CDH2 distribution by regulating clathrin-dependent endocytosis in the chicken paraxial mesoderm. Interestingly, the rostral compartment of S-I, which strongly expresses PAPC, shows high levels of punctate clathrin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1628–1638.
Published: 01 May 2015
...Robert J. Garriock; Ravindra B. Chalamalasetty; Mark W. Kennedy; Lauren C. Canizales; Mark Lewandoski; Terry P. Yamaguchi In the development of the vertebrate body plan, Wnt3a is thought to promote the formation of paraxial mesodermal progenitors (PMPs) of the trunk region while suppressing neural...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4285–4297.
Published: 15 November 2014
... 2014 © 2014. Published by The Company of Biologists Ltd 2014 bHLH transcription factor Paraxial mesoderm PSM Differentiation EMT Motility Wnt Embryonic stem cell Somite Mouse The process of vertebrate body formation provides an excellent opportunity to understand...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (20): 3848–3858.
Published: 15 October 2014
...Jiangang Zhao; Songhui Li; Suprita Trilok; Makoto Tanaka; Vanta Jokubaitis-Jameson; Bei Wang; Hitoshi Niwa; Naoki Nakayama Pluripotent embryonic stem cells (ESCs) generate rostral paraxial mesoderm-like progeny in 5-6 days of differentiation induced by Wnt3a and Noggin (Nog). We report...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (24): 4656–4665.
Published: 15 December 2012
... tail somites. Through its combined effects on gene expression and cell movement, Msgn1 (with Spt) plays a key role both in genesis of the paraxial mesoderm and in maintenance of the progenitor population from which it derives. Further insight into Msgn1 function comes from the timecourse...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1531–1541.
Published: 01 May 2010
... patterning, in which Wnt3a from the paraxial mesoderm induces posterior cell fates via direct activation of a crucial transcription factor in the overlying neural plate. * Author for correspondence ( dale@tx.technion.ac.il ) Competing interests statement The authors declare no competing financial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (10): 1823–1832.
Published: 15 May 2008
... plate mesoderm. † Author for correspondence (e-mail: per.lindahl@wlab.gu.se ) * Present address: Division of Vascular Surgery, University of Cologne,Cologne, Germany 17 3 2008 © 2008. 2008 Vascular smooth muscle cell Aorta Lateral plate mesoderm Paraxial mesoderm...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1253–1257.
Published: 01 April 2007
...,Tierra del Fuego, Argentina † Current address: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA 1 2 2007 © 2007. 2007 Myotome Anterior border cells Cell fate Paraxial mesoderm Somite Dermomyotome Zebrafish Fast muscle Pax7 Myogenesis Teleost...
Journal Articles
Journal: Development
Development (2006) 133 (19): 3767–3775.
Published: 01 October 2006
... in mesoderm development. Unlike Bmpr1a -null embryos, which fail to gastrulate, Bmpr-MORE embryos initiate gastrulation, but the recruitment of prospective paraxial mesoderm cells to the primitive streak is delayed. This delay causes a more proximal distribution of cells with paraxial mesoderm character...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (14): 3111–3124.
Published: 15 July 2003
... and amphibian embryos. Here, we analyze the molecular mechanisms of neural crest induction by the mesoderm in Xenopus embryos. Using a recombination assay, we show that prospective paraxial mesoderm induces a panel of neural crest markers ( Slug, FoxD3, Zic5 and Sox9 ),whereas the future axial mesoderm only...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2717–2728.
Published: 15 June 2003
... temporal activation of expression and the establishment of the correct anterior boundary in the paraxial mesoderm (somite 6/7). However, the Hoxb4 promoter is required to maintain this expression beyond 8.5 dpc. In addition, sequences within the 3′ untranslated region (region B)are necessary specifically...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3693–3704.
Published: 01 August 2002
... and her7 MOs individually produce distinguishable somitic phenotypes, but together mimic the b567 mutant phenotype at lower doses than the single injections ( Table 1 ) suggests that her1 and her7 have partially, but not completely, redundant functions. Paraxial mesoderm specification...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2255–2268.
Published: 15 June 2001
... environment. Results from experiments in which posterior neural segments and/or paraxial mesoderm segments were placed at different axial levels suggest that signals setting Hoxd10 expression form a decreasing posterior-to-anterior gradient. Our experiments do not, however, implicate adjacent paraxial...
Journal Articles
Journal: Development
Development (1988) 104 (Supplement): 209–220.
Published: 01 October 1988
...Antone G. Jacobson Well before the somites form, the paraxial mesoderm of vertebrate embryos is segmented into somitomeres. When newly formed, somitomeres are patterned arrays of mesenchymal cells, arranged into squat, bilaminar discs. The dorsal and ventral faces of these discs are composed...