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Keywords: Paraxial mesoderm
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Journal Articles
Journal: Development
Development (2022) 149 (11): dev196220.
Published: 6 June 2022
... and commitment to the generation of PRG4 -expressing permanent cartilage, has been developed from human pluripotent stem cells and characterized at the molecular level. Pluripotent stem cell Paraxial mesoderm Chondrocyte Hypertrophy Mineralization Joint Interzone Articular cartilage Ligament...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (10): dev183996.
Published: 26 May 2020
... Paraxial mesoderm Olig2 Pax7 Retinoic acid Somite The sonic hedgehog (Shh) protein plays fundamental roles in the development of the neural tube (NT) and somites ( Borycki et al., 1998 ; Briscoe, 2009 ; Cairns et al., 2008 ; Ericson et al., 1997a , b ; Gustafsson et al., 2002 ). Its...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (16): dev165431.
Published: 23 August 2018
.... Dyn.   235 , 1884 - 1894 . 10.1002/dvdy.20832 Aulehla , A. and Pourquié , O. ( 2010 ). Signaling gradients during paraxial mesoderm development . Cold Spring Harb. Perspect Biol.   2 , a000869 . 10.1101/cshperspect.a000869 Awaya , T. , Kato , T. , Mizuno , Y...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (6): dev157339.
Published: 19 March 2018
... Body skeletal muscles derive from the paraxial mesoderm, which forms in the posterior region of the embryo. Using microarrays, we characterize novel mouse presomitic mesoderm (PSM) markers and show that, unlike the abrupt transcriptome reorganization of the PSM, neural tube differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3808–3818.
Published: 15 October 2017
... lateral plate differentiation is profoundly altered. During this period, global mRNA levels are unchanged in the PSM, with only a minor subset of genes dysregulated. Together, our data strongly suggest that the TAF10-containing canonical TFIID and SAGA complexes are dispensable for early paraxial mesoderm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (12): 2104–2122.
Published: 15 June 2017
... of Biologists Ltd 2017 Summary: This Review discusses the mechanisms that underpin the formation of skeletal muscle during development and its recapitulation from pluripotent stem cells in vitro . Skeletal myogenesis Muscle differentiation Paraxial mesoderm Somite Dermomyotome Muscular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 664–676.
Published: 15 February 2017
.... , Mariani , B. D. and Tuan , R. S. ( 1997 ). Cloning and characterization of chicken Paraxis: a regulator of paraxial mesoderm development and somite formation . Dev. Biol.   189 , 95 - 111 . 10.1006/dbio.1997.8663 Barrios , A. , Poole , R. J. , Durbin , L. , Brennan , C...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1628–1638.
Published: 1 May 2015
...Robert J. Garriock; Ravindra B. Chalamalasetty; Mark W. Kennedy; Lauren C. Canizales; Mark Lewandoski; Terry P. Yamaguchi In the development of the vertebrate body plan, Wnt3a is thought to promote the formation of paraxial mesodermal progenitors (PMPs) of the trunk region while suppressing neural...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4285–4297.
Published: 15 November 2014
... , D. , Papaioannou , V. E. and Hadjantonakis , A.-K. ( 2012 ). Interaction of Wnt3a, Msgn1 and Tbx6 in neural versus paraxial mesoderm lineage commitment and paraxial mesoderm differentiation in the mouse embryo . Dev. Biol. 367 , 1 - 14 . 10.1016/j.ydbio.2012.04.012 Palmer...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (20): 3848–3858.
Published: 15 October 2014
...Jiangang Zhao; Songhui Li; Suprita Trilok; Makoto Tanaka; Vanta Jokubaitis-Jameson; Bei Wang; Hitoshi Niwa; Naoki Nakayama Pluripotent embryonic stem cells (ESCs) generate rostral paraxial mesoderm-like progeny in 5-6 days of differentiation induced by Wnt3a and Noggin (Nog). We report...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (24): 4656–4665.
Published: 15 December 2012
... tail somites. Through its combined effects on gene expression and cell movement, Msgn1 (with Spt) plays a key role both in genesis of the paraxial mesoderm and in maintenance of the progenitor population from which it derives. We thank Stephen Wilson, David Kimelman and Randall Moon for snail1a...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1531–1541.
Published: 1 May 2010
... patterning, in which Wnt3a from the paraxial mesoderm induces posterior cell fates via direct activation of a crucial transcription factor in the overlying neural plate. In late-gastrula stages, reducing Meis3 protein expression levels by either Wnt loss of function, or the Meis3 -MO also strongly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (10): 1823–1832.
Published: 15 May 2008
..., the expression was more widespread with staining in paraxial mesoderm cells and in the neural plate ( Fig. 1D,E ). Fig. 2. SMC differentiation is induced in lateral plate mesoderm-derived cells on the ventral side of the dorsal aorta at E9.5. ( A-D ) lacZ staining of stage- and location-matched...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1253–1257.
Published: 1 April 2007
...,Tierra del Fuego, Argentina † Current address: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA 1 2 2007 © 2007. 2007 Myotome Anterior border cells Cell fate Paraxial mesoderm Somite Dermomyotome Zebrafish Fast muscle Pax7 Myogenesis Teleost...
Journal Articles
Journal: Development
Development (2006) 133 (19): 3767–3775.
Published: 1 October 2006
... in mesoderm development. Unlike Bmpr1a -null embryos, which fail to gastrulate, Bmpr-MORE embryos initiate gastrulation, but the recruitment of prospective paraxial mesoderm cells to the primitive streak is delayed. This delay causes a more proximal distribution of cells with paraxial mesoderm character...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (14): 3111–3124.
Published: 15 July 2003
... and amphibian embryos. Here, we analyze the molecular mechanisms of neural crest induction by the mesoderm in Xenopus embryos. Using a recombination assay, we show that prospective paraxial mesoderm induces a panel of neural crest markers ( Slug, FoxD3, Zic5 and Sox9 ),whereas the future axial mesoderm only...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2717–2728.
Published: 15 June 2003
... temporal activation of expression and the establishment of the correct anterior boundary in the paraxial mesoderm (somite 6/7). However, the Hoxb4 promoter is required to maintain this expression beyond 8.5 dpc. In addition, sequences within the 3′ untranslated region (region B)are necessary specifically...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3693–3704.
Published: 1 August 2002
... to –25; her7b MO 5′-TTTCAGTCTGTGCCAGGATTTTCAT-3′ location: +1 to +25; ‡Author for correspondence (e-mail: amacher@uclink4.berkeley.edu ) 9 5 2002 © 2002. 2002 Paraxial mesoderm Presomitic mesoderm Somitogenesis Notch signaling her1 her7 Zebrafish...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2255–2268.
Published: 15 June 2001
... environment. Results from experiments in which posterior neural segments and/or paraxial mesoderm segments were placed at different axial levels suggest that signals setting Hoxd10 expression form a decreasing posterior-to-anterior gradient. Our experiments do not, however, implicate adjacent paraxial...
Journal Articles
Journal: Development
Development (1988) 104 (Supplement): 209–220.
Published: 1 October 1988
...Antone G. Jacobson Well before the somites form, the paraxial mesoderm of vertebrate embryos is segmented into somitomeres. When newly formed, somitomeres are patterned arrays of mesenchymal cells, arranged into squat, bilaminar discs. The dorsal and ventral faces of these discs are composed...