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Keywords: Paneth cell
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Journal Articles
Journal: Development
Development (2015) 142 (12): 2147–2162.
Published: 15 June 2015
... of Paneth cells – a Wnt-dependent cell type – is severely affected. Rab8a knockout crypts show an expansion of Lgr5 + and Hopx + cells in vivo . However, in vitro , the knockout enteroids exhibit significantly weakened growth that can be partly restored by exogenous Wnts or Gsk3β inhibitors. Immunogold...
Includes: Supplementary data