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Keywords: Paneth cell
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Journal Articles
Soumyashree Das, Shiyan Yu, Ryotaro Sakamori, Pavan Vedula, Qiang Feng, Juan Flores, Andrew Hoffman, Jiang Fu, Ewa Stypulkowski, Alexis Rodriguez, Radek Dobrowolski, Akihiro Harada, Wei Hsu, Edward M. Bonder, Michael P. Verzi, Nan Gao
Journal:
Development
Development (2015) 142 (12): 2147–2162.
Published: 15 June 2015
... of Paneth cells – a Wnt-dependent cell type – is severely affected. Rab8a knockout crypts show an expansion of Lgr5 + and Hopx + cells in vivo . However, in vitro , the knockout enteroids exhibit significantly weakened growth that can be partly restored by exogenous Wnts or Gsk3β inhibitors. Immunogold...
Includes: Supplementary data