...Frédéric Rosa; Nicolas Dray; Sébastien Bedu; Laure Bally-Cuif ABSTRACT Neural stem cells (NSCs) generate neurons over a lifetime in adult vertebrate brains. In the adult zebrafish pallium, NSCs persist long term through balanced fate decisions. These decisions include direct neuronal conversions...

...: BirthSeq allows the isolation and investigation of alive cells according to their birthdate, in any kind of tissue and vertebrate species. Neurogenesis Neocortex Birds Reptiles FACS sorting Single-cell RNA sequencing Progenitor cells Pallium In situ sequencing Ikerbasque, Basque...

... properties are linked, and to what extent they can be independently controlled by NSC maintenance pathways, is unresolved. We have previously identified Notch3 signalling as a major quiescence-promoting pathway in adult NSCs of the zebrafish pallium. We now show that Notch3 also controls NSC stemness. Using...

... in the developing mouse and chick pallium, whereas stage-specific binary functions of Pax6 in neurogenesis are unique to mouse neuronal progenitors, consistent with Pax6-dependent temporal regulation of Notch signaling. Furthermore, we identified that Pax6-dependent enhancer activity of Dbx1 is extensively...

.... In placental mammals, this proliferative cell population can be subdivided into several groups that include Tbr2 + intermediate progenitors and basal radial glial cells (bRGs). Here, we report that basal progenitors in the developing avian pallium show unique morphological and molecular characteristics...

... divisions across the entire germinal zone of the adult pallium, and to highlight regional differences in these parameters. 5 2 2015 20 8 2015 * Authors for correspondence ( [email protected] ; [email protected] ) Competing interests The authors...

... about their origin and development. Previous studies suggest that they originate in the medial ganglionic eminence of the telencephalic subpallium; however, our results identified Tbr1 -expressing, reelin-positive neurons migrating from the ventral pallium to the subpallium that differentiate...

.... The expression spans the pallio-subpallial boundary, which separates the dorsal (i.e. pallium) and ventral (i.e. subpallium) telencephalon. Despite being expressed on both sides of the pallio-subpallial boundary, Tlx homozygous mutants display alterations in the development of this boundary. These alterations...