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Keywords: PKC
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Journal Articles
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Reproductive biology
Journal: Development
Development (2021) 148 (14): dev199461.
Published: 16 July 2021
... that ubiquitylation may be involved in GlyT1a degradation. The clathrin inhibitor blocked GlyT1a internalization. Strikingly, the protein kinase C (PKC) activator triggered the heterochronic internalization of GlyT1a; the PKC inhibitor markedly blocked GlyT1a endocytosis. Lastly, clathrin inhibition completely...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (20): 3806–3816.
Published: 15 October 2016
...Tetsuhisa Otani; Yosuke Ogura; Kazuyo Misaki; Takuya Maeda; Akiyo Kimpara; Shigenobu Yonemura; Shigeo Hayashi Signaling molecules have pleiotropic functions and are activated by various extracellular stimuli. Protein kinase C (PKC) is activated by diverse receptors, and its dysregulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (20): 3806–3816.
Published: 15 October 2016
...Tetsuhisa Otani; Yosuke Ogura; Kazuyo Misaki; Takuya Maeda; Akiyo Kimpara; Shigenobu Yonemura; Shigeo Hayashi Signaling molecules have pleiotropic functions and are activated by various extracellular stimuli. Protein kinase C (PKC) is activated by diverse receptors, and its dysregulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 575–584.
Published: 15 February 2009
... show that two parallel pathways are involved in the neuralising activity of Syn4: FGF/ERK, which is sensitive to dominant-negative FGF receptor and to the inhibitors SU5402 and U0126, and a PKC pathway, which is dependent on the intracellular domain of Syn4. Neural induction by Syn4 through the PKC...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (16): 2739–2746.
Published: 15 August 2008
...., Yoshinaga, S., Takeya, R., Suzuki, N. N., Horiuchi,M., Kohjima, M., Sumimoto, H. and Inagaki, F. ( 2005 ). Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains. J. Biol. Chem. 280 , 9653 -9661. Hutterer, A., Betschinger, J., Petronczki, M. and Knoblich, J...
Journal Articles
Journal: Development
Development (2000) 127 (23): 5021–5031.
Published: 1 December 2000
... for correspondence (e-mail: ohnos@med.yokohama-cu.ac ) 02 09 200 10 09 2000 © 2000 by Company of Biologists 2000 Xenopus laevis PKC ASIP PAR Asymmetry Polarity Oocyte Meiotic maturation The asymmetric localization of cytoplasmic components is the basis for the cell fate...
Journal Articles
Journal: Development
Development (2000) 127 (22): 4891–4903.
Published: 15 November 2000
... in mice lacking MARCKS, the major substrate of protein kinase C (PKC), and we have found that p190 RhoGAP is also a PKC substrate in vivo. Upon either direct activation of PKC or in response to integrin engagement, p190 RhoGAP is rapidly translocated to regions of membrane ruffling, where it colocalizes...
Journal Articles
Journal: Development
Development (1997) 124 (14): 2751–2760.
Published: 15 July 1997
... genes. The sensitivity of the upregulation of neurectodermal markers to GF109203X indicates that the activity of a calcium activated protein kinase C (PKC) is also required. Furthermore ectopic expression of mouse eIF4AII mRNA upregulates the endogenous eIF4AII gene by a process that requires...
Journal Articles
Journal: Development
Development (1995) 121 (5): 1507–1517.
Published: 1 May 1995
... by Company of Biologists 1995 kidney development morphogenesis branching glycosaminoglycans PKC hepatocyte growth factor mouse Little is known about the mechanisms that regulate epithelial differentiation and morphogenesis during embryonic development (for reviews see Fleming, 1992...