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Keywords: PGC clones
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Journal Articles
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells
Available to PurchaseJiyoung Lee, Kimiko Inoue, Ryuichi Ono, Narumi Ogonuki, Takashi Kohda, Tomoko Kaneko-Ishino, Atsuo Ogura, Fumitoshi Ishino
Journal:
Development
Development (2002) 129 (8): 1807–1817.
Published: 15 April 2002
... with the loss of their imprinted monoallelic expression was also observed. Analysis of DNA methylation in day 10.5 to day 12.5 PGCs demonstrated that PGC clones represented the DNA methylation status of donor PGCs well. These findings provide strong evidence that the erasure process of genomic imprinting memory...
