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Journal Articles

The PDZ-GEF Dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo

Sven Huelsmann, Christina Hepper, Daniele Marchese, Christian Knöll, Rolf Reuter
Journal: Development
Development (2006) 133 (15): 2915–2924.
https://doi.org/10.1242/dev.02449
Published: 1 August 2006
... identified the Drosophila PDZ G-nucleotide exchange factor (PDZ-GEF)Dizzy as a component essential for normal macrophage migration. In mutants lacking Dizzy, macrophages have smaller cellular protrusions, and their migration is slowed down significantly. This phenotype appears to be cell-autonomous...
View articletitled, The PDZ-GEF Dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo
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