...-A and PDGF-B), and the alpha and beta subunits of the PDGF receptor (PDGFR αR and PDGF βR). We have also visualized PDGF-A protein in these tissues by immunohistochemistry. In the retina, PDGF-A mRNA is present in pigment epithelial cells, ganglion neurons and a subset of amacrine neurons. PDGF-A transcripts...

... (beneath the foramen of Monro). Our data demonstrate that gene expression and cell fate can be regulated with exquisite spatial resolution along the dorsoventral axis of the mammalian neural tube. 26 10 1992 © 1993 by Company of Biologists 1993 PDGF receptors rat CNS glial cells...

... + cells persist in the adult CNS. PDGF- α R is also expressed strongly in the meningeal membranes and choroid plexus, and in the inner limiting membrane of the retina. 02 03 1992 © 1992 by Company of Biologists 1992 PDGF receptors rat CNS glial cells development in situ...

... to show that O-2A progenitor cells have PDGF receptors, suggesting that these cells respond directly to PDGF. The receptors resemble the type A PDGF receptor previously described on human fibroblasts and are initially retained when progenitor cells stop dividing and develop in vitro into oligodendrocytes...