... in the development of cardiac and cephalic NCCs and provides a model for the study of aberrant NCC development. † Author for correspondence (e-mail: [email protected] ) 31 10 2002 © 2003. 2003 Chimeric analysis Cre-loxP recombination Neural crest PDGF receptor Mouse...

... contributions to the work * Author for correspondence ( [email protected] ) 7 January 1999 11 November 1998 © 1999 by Company of Biologists 1999 Central nervous system Oligodendrocyte Progenitor cell PDGF PDGF receptor Knockout mouse PLP/DM-20 MBP Myelin...

... pathways are involved in gastrulation and spicu-logenesis in the Lytechinus pictus embryo. Here we show that expression of the human PDGF receptor-β lacking the cytoplasmic domain disrupted development in a manner consistent with a dominant/negative mechanism. The truncated PDGF receptor-β inhibited gut...

... , A. J. , Tomlinson , J. E. , Seroogy , J. J. , Wolf , D. L. , LaRochelle , W. J. and Giese , N. A. ( 1993 ). Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptors . J. Biol. Chem. 268 , 3625 – 3631 . 10.1016/S0021-9258...

... that the SH3 domain also functions in the intramolecular regulation of Src activity. * Author for correspondence © The Company of Biologists Limited 1993 1993 protein tyrosine kinase Src PDGF receptor Csk S. pombe The Src family of protein tyrosine kinases comprises at least nine...

... mesenchyme ( Fig. 3 ). Similarly, the thickness of the cornea in E16 Ph/Ph embryos was approximately half that of normal corneas. * To whom correspondence should be addressed 05 02 1992 © 1992 by Company of Biologists 1992 neural crest PDGF receptor PDGF Patch mouse embryo...

... together suggest that the α PDGF receptor may be required for the normal development of visceral endoderm and mesoderm derivatives. * Author for correspondence 24 02 1992 © 1992 by Company of Biologists 1992 PDGF receptor embryogenesis in situ hybridization Ph mutation...