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Keywords: PCM
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Journal Articles
Journal: Development
Development (2021) 148 (20): dev198416.
Published: 19 October 2021
...Lisa Stenzel; Alina Schreiner; Elisa Zuccoli; Sim Üstüner; Judith Mehler; Esther Zanin; Tamara Mikeladze-Dvali ABSTRACT Correct cell division relies on the formation of a bipolar spindle. In animal cells, microtubule nucleation at the spindle poles is facilitated by the pericentriolar material (PCM...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (5): dev162461.
Published: 09 March 2018
... it is mainly located, has remained elusive. Here, we show that Drosophila Mbf1 associates with E(z) mRNA and protects it from degradation by the exoribonuclease Pacman (Pcm), thereby ensuring Polycomb silencing. In genetic studies, loss of mbf1 function enhanced a Polycomb phenotype in Polycomb group mutants...
Includes: Supplementary data