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Keywords: PAX7
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Journal Articles
Journal: Development
Development (2020) 147 (19): dev185975.
Published: 09 October 2020
...Maud Wurmser; Nathalie Chaverot; Rouba Madani; Hiroshi Sakai; Elisa Negroni; Josiane Demignon; Benjamin Saint-Pierre; Vincent Mouly; Helge Amthor; Stephen Tapscott; Carmen Birchmeier; Shahragim Tajbakhsh; Fabien Le Grand; Athanassia Sotiropoulos; Pascal Maire ABSTRACT Pax7 expression marks stem...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev187344.
Published: 26 June 2020
...Ziad Al Tanoury; Jyoti Rao; Olivier Tassy; Bénédicte Gobert; Svetlana Gapon; Jean-Marie Garnier; Erica Wagner; Aurore Hick; Arielle Hall; Emanuela Gussoni; Olivier Pourquié ABSTRACT Satellite cells (SC) are muscle stem cells that can regenerate adult muscles upon injury. Most SC originate from PAX7...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (10): dev183996.
Published: 26 May 2020
... Paraxial mesoderm Olig2 Pax7 Retinoic acid Somite The sonic hedgehog (Shh) protein plays fundamental roles in the development of the neural tube (NT) and somites ( Borycki et al., 1998 ; Briscoe, 2009 ; Cairns et al., 2008 ; Ericson et al., 1997a , b ; Gustafsson et al., 2002 ). Its...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (17): 3691–3702.
Published: 01 September 2013
... elevated as the neural folds (NFs) form and fuse in the dorsal region of the closed neural tube, from where NC cells emigrate. In chick embryos, Pax7 is an early marker, and necessary component of NC development. Unlike other early NPB markers, which are co-expressed in lateral ectoderm, medial neural...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (24): 4536–4548.
Published: 15 December 2012
... cells with high Pax7 expression. By genetically modulating Notch activity, we demonstrate that activated Notch (NICD) blocks terminal differentiation in an Rbpj-dependent manner that is sufficient to sustain stem/progenitor cells throughout embryogenesis, despite the absence of committed progeny...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 2845–2856.
Published: 15 August 2012
... cell division ( Heslop et al., 2000 ; Wakeford et al., 1991 ). Finally, prevention of mature miRNA production in satellite cells via targeted inactivation of the miRNA-processing enzyme Dicer, causes most satellite cells to exit quiescence and undergo apoptosis in Pax7 CreER/+ : Dicer flox/flox...
Journal Articles
Journal: Development
Development (2012) 139 (2): 289–300.
Published: 15 January 2012
... border Gastrulation Pax7 Chick The neural crest (NC) is a population of multipotent embryonic cells that migrates from the dorsal neural tube to give rise to a diverse array of derivatives, including melanocytes, sensory neurons of the peripheral nervous system, and most of the bone and...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3639–3646.
Published: 01 September 2011
... repair that is widely held to be accomplished by the satellite cells lying between the muscle fiber plasmalemma and the basement membrane. Cell transplantation and lineage-tracing studies have demonstrated that Pax7-expressing (Pax7 + ) satellite cells can repair damaged muscle tissue repeatedly after...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3625–3637.
Published: 01 September 2011
... Tcf4, a newly identified fibroblast marker, and Pax7, a satellite cell marker, we found that after injury satellite cells and fibroblasts rapidly proliferate in close proximity to one another. To test the role of satellite cells and fibroblasts in muscle regeneration in vivo, we created Pax7 CreERT2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (5): 821–830.
Published: 01 March 2011
... express Pax7, but overexpression of Pax7 in blastomeres of whole embryos that populate the myogenic areas does not induce the formation of additional satellite cells. Moreover, a dominant-negative construct, Pax7EnR , does not reduce satellite cell formation. Neither Pax7 nor other myogenic transcription...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 219–229.
Published: 15 January 2009
... pits are capable of inducing bone, cartilage and ectopic PAX7 expression, but these effects were only observed in the facial grafts. Facial mesenchyme also supported the initial projection of the olfactory nerve and differentiation of the olfactory epithelium. Thus, the nasal placode has two roles: as...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (11): 2083–2093.
Published: 01 June 2007
... for regeneration. We further tracked single nuclear-GFP-labeled cells as they proliferated during regeneration, observing their spatial distribution, and ultimately their expression of the progenitor markers PAX7 and PAX6. Most progenitors generate descendents that expand along the anterior/posterior...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (7): 1253–1257.
Published: 01 April 2007
... transcription factor Pax7. Some remain on the external surface and some incorporate into the fast myotome, apparently by moving between differentiated slow fibres. The posterior cells of the somite, by contrast, elongate into medial muscle fibres. The surprising movement of the anterior somite cells to the...
Journal Articles
Journal: Development
Development (2006) 133 (12): 2303–2313.
Published: 15 June 2006
... contains many muscle satellite cells. They are active in DNA replication, whereas the myonuclei are not. As in mammals, the satellite cells express pax7 . We show that a domain-swapped construct, pax7EnR , can antagonize pax7 function. Transgenic tadpoles were prepared containing pax7EnR driven by a heat...
Journal Articles
Journal: Development
Development (2006) 133 (6): 1101–1112.
Published: 15 March 2006
... Epithelial to mesenchymal transition Muscle Myod Myf5 Pax3 Pax7 Somite By contrast, we report that N-cadherin-mediated adhesion is not necessary for establishment of the first wave of pioneer fibers. This might be related to the early downregulation of the protein that is...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3243–3253.
Published: 15 July 2005
... embryonic neural tube development, including Pax6 , Pax7 and Msx1 . Furthermore, the expression of Sonic hedgehog ( Shh ) is localized to the ventral floor plate domain in both mature and regenerating spinal cord. Patched1 receptor expression indicated that hedgehog signaling occurs not only within the...
Journal Articles
Journal: Development
Development (2005) 132 (4): 689–701.
Published: 15 February 2005
... that maintain expression of PAX7,PAX3 and FREK. Given this dual fate, we asked whether single dermomyotome precursors generate both dermal and mitotic myoblast precursors, or alternatively, whether these cell types derive from distinct epithelial founders. Inovo clonal analysis revealed that single...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (3): 447–458.
Published: 01 February 2005
... different as the cloacal anlage extends from the ventral muscle mass towards the cloacal tubercle. Pax3, Pax7 and MyoD are expressed at the same level both at the leading and trailing edges of the cloacal anlage and thus resemble a myotomal extension. This situation is similar to the mode of development...
Journal Articles
Journal: Development
Development (2002) 129 (3): 573–583.
Published: 01 February 2002
...Roy C. Mootoosamy; Susanne Dietrich Most head muscles arise from the pre-otic axial and paraxial head mesoderm. This tissue does not form somites, yet expresses the somitic markers Lbx1 , Pax7 and Paraxis in a regionalised fashion. The domain set aside by these markers provides the lateral rectus...
Journal Articles
Journal: Development
Development (2001) 128 (20): 4069–4077.
Published: 15 October 2001
...Eiji Matsunaga; Isato Araki; Harukazu Nakamura Pax3/7 is expressed in the alar plate of the mesencephalon. The optic tectum differentiates from the alar plate of the mesencephalon, and expression of Pax3/7 is well correlated to the tectum development. To explore the function of Pax3 and Pax7 in the...