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Keywords: P-TEFb
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Journal Articles
The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors
Available to PurchaseMichael J. Jurynec, Xiaoying Bai, Brent W. Bisgrove, Haley Jackson, Alex Nechiporuk, Rebecca A. S. Palu, Hannah A. Grunwald, Yi-Chu Su, Kazuyuki Hoshijima, H. Joseph Yost, Leonard I. Zon, David Jonah Grunwald
Journal:
Development
Development (2019) 146 (24): dev180133.
Published: 16 December 2019
... progenitor development is affected similarly. Development of mutant NC could be rescued by additional loss of positive transcription elongation factor b (P-TEFb) activity, a key factor in promoting transcription elongation. Consistent with the interpretation that inhibiting/delaying expression of some genes...
Includes: Supplementary data
