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Keywords: Oxygen
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Journal Articles
Journal: Development
Development (2021) 148 (4): dev194787.
Published: 15 February 2021
...Keishi Otsu; Hiroko Ida-Yonemochi; Shojiro Ikezaki; Masatsugu Ema; Jiro Hitomi; Hayato Ohshima; Hidemitsu Harada ABSTRACT Stem cells are maintained in specific niches that strictly regulate their proliferation and differentiation for proper tissue regeneration and renewal. Molecular oxygen (O 2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (4): dev156257.
Published: 14 February 2018
...Peter V. Lidsky; Konstantin A. Lukyanov; Tvisha Misra; Björn Handke; Alexander S. Mishin; Christian F. Lehner ABSTRACT Oxygen concentrations vary between tissues of multicellular organisms and change under certain physiological or pathological conditions. Multiple methods have been developed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (4): 566–574.
Published: 15 February 2016
... from the hyperplasia. When SSCs that underwent the SSC-propagating step for 1 month were transferred onto Sertoli feeder cells, they differentiated into functional sperm that gave rise to offspring. Oxygen at the concentration of air proved to be detrimental for sperm differentiation from SSCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (14): 2405–2412.
Published: 15 July 2015
... skeletal muscle disease. It is now widely appreciated that nutrients, such as molecular oxygen (O 2 ), modulate skeletal muscle formation. During early stages of development and regeneration, skeletal muscle progenitors reside in low O 2 environments before local blood vessels and differentiated muscle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (4): 672–680.
Published: 15 February 2015
...Idit Eshkar-Oren; Sharon Krief; Napoleone Ferrara; Alison M. Elliott; Elazar Zelzer Blood vessels serve as key regulators of organogenesis by providing oxygen, nutrients and molecular signals. During limb development, programmed cell death (PCD) contributes to separation of the digits...
Journal Articles
Journal: Development
Development (2007) 134 (18): 3349–3358.
Published: 15 September 2007
... also have other hydroxylation substrates( Kuznetsova et al., 2003 ). Hypoxia might regulate PHD activity directly via O 2 starvation, or indirectly via reactive oxygen species( Kaelin, 2005a ) or effects on other regulatory factors and substrates, such as Krebs cycle intermediates( Briere et al., 2005...
Journal Articles
Journal: Development
Development (2006) 133 (4): 751–759.
Published: 15 February 2006
... line undergoes accelerated growth when cultured in an atmosphere of 2% O 2 ( Kilburn et al., 2000 ). Physiologically, trophoblasts do not live at 20% O 2 , used in our experimental model to provide an oxygenated state, but they do experience levels near 2% during the first trimester. We hypothesized...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1855–1862.
Published: 15 April 2005
... provide feedback signals that trigger astrocyte differentiation – marked by cessation of cell division, upregulation of glial fibrillary acidic protein (GFAP) and downregulation of VEGF. We prevented retinal vessel development by raising newborn mice in a high-oxygen atmosphere, which leads, paradoxically...