.... Wingless Wnt Shavenbaby Ovo SoxNeuro Denticle Morphogenesis Drosophila melanogaster Information from signaling pathways must be interpreted and modulated for the proper execution of cellular events during development. Much of developmental biology research has focused on the signaling...

...Jining Lü; Brian Oliver ABSTRACT Evolutionarily conserved ovo loci encode developmentally regulated, sequence-specific, DNA-binding, C 2 H 2 -zinc-finger proteins required in the germline and epidermal cells of flies and mice. The direct targets of OVO activity are not known. Genetic experiments...

... cells to support oogenesis. In addition, the ovarian tumor function required for female germline differentiation is dependent on the activity of another germline gene, ovo , whose regulation is transformer- independent. These and other data indicate that ovarian tumor plays a central role...

...Maryvonne Mével-Ninio; Eric Fouilloux; Isabelle Guénal; Alain Vincent ABSTRACT The Drosophila ovo gene, which encodes a putative transcription factor (Ovo) with TFIIIA-like zinc fingers, is required for female germline survival and proper oogenesis. Three dominant female-sterile ovo D mutations...

... in this interaction, we examined whether changes in the sexual identity of the soma affected the function of the ovarian tumor ( otu ) and ovo genes. These genes are required cell autonomously in the female germline for germ cell proliferation and differentiation. Mutations in otu and ovo cause a range of ovarian...

... of these sex determination cues are required for female-specific Sex-lethal + function in germ cells. The ovo + locus encodes zinc finger protein(s) required for female-specific splicing of Sex-lethal + pre-mRNA, making ovo + a candidate function acting between the two principal cues and Sex-lethal + . We have...