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Keywords: Otx-2
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Journal Articles

The homeobox gene, Xanf-1 , can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo

Galina V. Ermakova, Eugenia M. Alexandrova, Olga V. Kazanskaya, Oleg L. Vasiliev, Maria W. Smith, Andrey G. Zaraisky
Journal: Development
Development (1999) 126 (20): 4513–4523.
https://doi.org/10.1242/dev.126.20.4513
Published: 15 October 1999
... into abnormal brain outgrowths. At the same time, Xanf-1 can inhibit terminal differentiation of primary neurones. We also show that, during gastrula/ neurula stages, the exogenous Xanf-1 can downregulate four transcription regulators, XBF-1, Otx-2, Pax-6 and the endogenous Xanf-1 , that are expressed...
View articletitled, The homeobox gene, Xanf-1 , can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo
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Journal Articles

Gene activation during early stages of lens induction in Xenopus

Carol A. Zygar, T. Les Cook, Jr, Robert M. Grainger
Journal: Development
Development (1998) 125 (17): 3509–3519.
https://doi.org/10.1242/dev.125.17.3509
Published: 1 September 1998
... play a role in lens bias and specification, and we focus on these roles here. Fate mapping shows that the transcriptional regulators Otx-2, Pax-6 and Sox-3 are expressed in the presumptive lens ectoderm prior to lens differentiation. Otx-2 appears first, followed by Pax-6 , during the stages of lens...
View articletitled, Gene activation during early stages of lens induction in Xenopus
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Journal Articles

Patterning of the embryo along the anterior-posterior axis: the role of the caudal genes

Michal Epstein, Graciela Pillemer, Ronit Yelin, Joel K. Yisraeli, Abraham Fainsod
Journal: Development
Development (1997) 124 (19): 3805–3814.
https://doi.org/10.1242/dev.124.19.3805
Published: 1 October 1997
...Michal Epstein; Graciela Pillemer; Ronit Yelin; Joel K. Yisraeli; Abraham Fainsod ABSTRACT Patterning along the anterior-posterior axis takes place during gastrulation and early neurulation. Homeobox genes like Otx-2 and members of the Hox family have been implicated in this process. The caudal...
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