1-11 of 11
Keywords: Otx
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2021) 148 (12): dev198754.
Published: 14 June 2021
... and the transcription factor Otx are required for the expression of Fer2 in the dopaminergic cell lineage. Our findings establish the cellular and molecular framework for fully understanding the commitment to dopaminergic cells in the simple chordate brain. Table 1. The average number of cells expressing Fer2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (22): dev171405.
Published: 21 November 2019
... of ectopic pineal progenitors. We also demonstrate that fibroblast growth factors (FGFs) position the pineal progenitor domain within the non-neural border by repressing pineal fate and that the Otx transcription factors promote pinealogenesis by inhibiting this FGF activity. The non-neural origin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (16): 2792–2800.
Published: 15 August 2015
... studies show that Otx2 is essential for spatial restriction of the sensory domain in the mammalian cochlea. Inner ear Cochlea Otx Myc Organ of Corti Mouse Otx2 , a murine ortholog of the Drosophila orthodenticle ( otd ; ocelliless – FlyBase) gene, encodes a transcription factor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (17): 2939–2949.
Published: 01 September 2010
... conserved among tetrapods and unexpectedly directed all the Emx2 expression in forebrain: caudal forebrain primordium at E8.5, dorsal telencephalon at E9.5-E10.5 and the cortical ventricular zone after E12.5. Otx, Tcf, Smad and two unknown transcription factor binding sites were essential to all...
Journal Articles
Journal: Development
Development (2010) 137 (6): 963–974.
Published: 15 March 2010
... , the ceh-36 Otx homeobox gene is expressed in the AWC sensory neurons throughout postembryonic development, and regulates terminal differentiation of this neuronal subtype. Here, we show that the HMX/NKX homeodomain protein MLS-2 regulates ceh-36 expression specifically in the AWC neurons. Consequently...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (7): 1347–1357.
Published: 01 April 2006
... for correspondence (e-mail: t.whitfield@sheffield.ac.uk ) 1 2 2006 © 2006. 2006 Lamprey Zebrafish Agnathan Gnathostome Inner ear Otic vesicle Macula follistatin ptc otx Evolution Placode Hair cell Planar polarity pattern The vertebrate inner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (7): 1663–1674.
Published: 01 April 2005
... show no detectable sequence conservation in the non-coding regions of studied orthologous genes. To address how a common developmental program can be maintained without detectable cis - regulatory sequence conservation, we compared in both species the regulation of Otx , a gene with a shared complex...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (11): 2365–2373.
Published: 01 June 2003
... and an intervening midbrain/hindbrain boundary region, which are characterized by the specific expression of the Otx, Hox and Pax2/5/8 genes, respectively. We show that the embryonic brain of the fruitfly Drosophila melanogaster expresses all three sets of homologous genes in a similar tripartite pattern. Thus...
Journal Articles
Journal: Development
Development (2003) 130 (7): 1281–1294.
Published: 01 April 2003
... ) 10 12 2002 © 2003. 2003 Retinal specification Cell fate otd Otx XOtx2 XOtx5 XOtx5b Bipolar cell Photoreceptor VP16 Engrailed Xenopus laevis Opsin Lipofection These results also suggest that the N-terminal and HD regions of these proteins are not sufficient...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4393–4404.
Published: 15 November 2001
...), which function in specifying vegetal fates. Morpholino Transcriptional repressor Embryonic axes Otx β-catenin Sea urchin © 2001. 2001 13 8 2001 *Author for correspondence (e-mail: langerer@mail.rochester.edu ) Full-length SpGsc cDNA was isolated as described...
Journal Articles
Journal: Development
Development (2001) 128 (13): 2433–2450.
Published: 01 July 2001
... of midbrain/hindbrain development, yet relatively little is known about forebrain organization. Nested expression among Otx and Emx genes has implicated their roles in rostral brain regionalization, but single mutant phenotypes of these genes have not provided sufficient information. In order to genetically...