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Keywords: Otoferlin
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Journal Articles
He Zhang, Hong Pan, Changyang Zhou, Yu Wei, Wenqin Ying, Shuting Li, Guangqin Wang, Chao Li, Yifei Ren, Gen Li, Xu Ding, Yidi Sun, Geng-Lin Li, Lei Song, Yixue Li, Hui Yang, Zhiyong Liu
Journal:
Development
Development (2018) 145 (20): dev168906.
Published: 17 October 2018
... individually mutated vGlut3 ( Slc17a8 ), otoferlin ( Otof ) and prestin ( Slc26a5 ), three genes needed for normal hearing function. Finally, we successfully disrupted vGlut3 , Otof and prestin simultaneously. Our results show that CRISPR-stop can efficiently generate single or triple homozygous F0 mouse...
Includes: Supplementary data
