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Keywords: Otic placode
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Journal Articles
Journal: Development
Development (2018) 145 (4): dev160325.
Published: 21 February 2018
... methylations in the human genome . Cell   129 , 823 - 837 . 10.1016/j.cell.2007.05.009 Betancur , P. , Sauka-Spengler , T. and Bronner , M. ( 2011 ). A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs . Development (Cambridge...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 245–257.
Published: 15 January 2012
... – are orchestrated by gradients of signaling molecules. * Authors for correspondence ( akgroves@bcm.edu ; dfekete@purdue.edu ) Competing interests statement The authors declare no competing financial interests. © 2012. 2012 Otic placode Morphogen Inner ear Cochlea Otocyst...
Journal Articles
Journal: Development
Development (2008) 135 (13): 2251–2261.
Published: 1 July 2008
...Chathurani S. Jayasena; Takahiro Ohyama; Neil Segil; Andrew K. Groves The inner ear derives from a patch of ectoderm defined by expression of the transcription factor Pax2. We recently showed that this Pax2 + ectoderm gives rise not only to the otic placode but also to the surrounding cranial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (13): 2449–2458.
Published: 1 July 2007
...% in the presence of 10 nM RA( Fig. 1D-F ). At the 12-somite stage, when the placode was outlined by cldna expression in control embryos, the otic placode was reduced in size in RA-signaling-depleted embryos, whereas excess RA led to a size increase( Fig. 1G-I ). Use of pax8 expression, which is initiated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (12): 2369–2378.
Published: 15 June 2007
... for correspondence (e-mail: n.daudet@ucl.ac.uk ) * These authors contributed equally to this work 26 3 2007 © 2007. 2007 Notch signalling Serrate Delta Chick embryo Inner ear Otic placode Neuroblasts Hair cell Lateral inhibition Lateral induction The vertebrate inner ear...
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (5): 865–875.
Published: 1 March 2006
...Takahiro Ohyama; Othman A. Mohamed; Makoto M. Taketo; Daniel Dufort; Andrew K. Groves The otic placode, the anlagen of the inner ear, develops from an ectodermal field characterized by expression of the transcription factor Pax2 . Previous fate mapping studies suggest that these Pax2 + cells...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (20): 5091–5102.
Published: 15 October 2004
...Stefan Hans; Dong Liu; Monte Westerfield The vertebrate inner ear arises from an ectodermal thickening, the otic placode, that forms adjacent to the presumptive hindbrain. Previous studies have suggested that competent ectodermal cells respond to Fgf signals from adjacent tissues and express two...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1755–1763.
Published: 15 April 2004
...Natasha Saint-Germain; Young-Hoon Lee; Yanhui Zhang; Thomas D. Sargent; Jean-Pierre Saint-Jeannet The vertebrate inner ear develops from a thickening of the embryonic ectoderm, adjacent to the hindbrain, known as the otic placode. All components of the inner ear derive from the embryonic otic...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2543–2554.
Published: 1 June 2003
...Robert M. Nissen; Jizhou Yan; Adam Amsterdam; Nancy Hopkins; Shawn M. Burgess We identified four insertional alleles of foxi one ( foo ),an embryonic lethal mutation in zebrafish that displays defects in both otic placode and the jaw. In foo/foo embryos the otic placode is split into two smaller...
Journal Articles
Journal: Development
Development (2003) 130 (5): 929–940.
Published: 1 March 2003
...Keely S. Solomon; Tetsuhiro Kudoh; Igor B. Dawid; Andreas Fritz The otic placode is a transient embryonic structure that gives rise to the inner ear. Although inductive signals for otic placode formation have been characterized, less is known about the molecules that respond to these signals within...
Journal Articles
Journal: Development
Development (2002) 129 (13): 3127–3136.
Published: 1 July 2002
... in concert and their importance in placode formation is only revealed by inactivating both paralogs. *Author for correspondence (e-mail: afritz@biology.emory.edu ) 10 4 2002 © 2002. 2002 Zebrafish dlx3 dlx7 Otic placode Olfactory placode The vertebrate ear and nose...
Journal Articles
Journal: Development
Development (2000) 127 (16): 3489–3499.
Published: 15 August 2000
... of the inner ear, the otic placode. Pax-2, Sox- 3, BMP-7 and Notch are all expressed in placodal ectoderm from the 4-5 somite stage (ss) onwards, well before the otic placode becomes morphologically visible at the 12-14ss. We have used these four molecular markers to show that cranial ectoderm becomes...
Journal Articles
Journal: Development
Development (2000) 127 (10): 2011–2019.
Published: 15 May 2000
.... These results demonstrate that a single gene can induce inner ear fate and reveal an unexpectedly widespread competence of the surface ectoderm to form sensory placodes in higher vertebrates. Otic placode Otic vesicle Fibroblast growth factor HSV-1 Ectopic expression Chicken The head ectoderm...
Journal Articles
Journal Articles
Journal: Development
Development (1988) 103 (Supplement): 185–193.
Published: 1 September 1988
...Thomas R. Van De Water ABSTRACT Statoacoustic ganglion neurones (SAG) are produced by the same group of cells (otic placode) that produce all of the receptor ceils that populate the sensory areas of the inner ear. The observation that ingrowth of SAG neurites to presumptive sensory areas...