... in the embryonic zebrafish telencephalon. Using a homozygote endogenous Her6:Venus reporter and 4D single-cell tracking, we show that Her6 oscillates in neural telencephalic progenitors and that the fusion of protein destabilisation (PEST) domain alters its expression dynamics, causing most cells to downregulate...

... neighboring cells during development and homeostasis. Notch Oscillations Lateral inhibition Patterning United States-Israel Binational Science Foundation http://dx.doi.org/10.13039/501100001742 2017245 Israel Science Foundation http://dx.doi.org/10.13039/501100003977 1343...

... unseen signaling dynamics in single pluripotent cells, which alternate between oscillatory and non-oscillatory ERK activity. ERK dynamics change with ligand concentration, cell cycle and differentiation state. FGF/ERK signaling Cell cycle Mouse embryonic stem cells Oscillations Signal...

...Julia Duque; Nicole Gorfinkiel In this work, we combine genetic perturbation, time-lapse imaging and quantitative image analysis to investigate how pulsatile actomyosin contractility drives cell oscillations, apical cell contraction and tissue closure during morphogenesis of the amnioserosa...

...Nathan P. Shih; Paul François; Emilie A. Delaune; Sharon L. Amacher The formation of reiterated somites along the vertebrate body axis is controlled by the segmentation clock, a molecular oscillator expressed within presomitic mesoderm (PSM) cells. Although PSM cells oscillate autonomously...

...Robert A. Bone; Charlotte S. L. Bailey; Guy Wiedermann; Zoltan Ferjentsik; Paul L. Appleton; Philip J. Murray; Miguel Maroto; J. Kim Dale During somitogenesis, epithelial somites form from the pre-somitic mesoderm (PSM) in a periodic manner. This periodicity is regulated by a molecular oscillator...