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1-11 of 11
Keywords: Organiser
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Journal Articles
Katie Abley, Pierre Barbier De Reuille, David Strutt, Andrew Bangham, Przemyslaw Prusinkiewicz, Athanasius F. M. Marée, Verônica A. Grieneisen, Enrico Coen
Journal:
Development
Development (2013) 140 (10): 2061–2074.
Published: 15 May 2013
.... Polarity is anchored to tissues through organisers located at boundaries. We show how this intracellular partitioning-based framework can be applied to both plant and animal systems, allowing different processes to be placed in a common evolutionary and mechanistic context. We begin with an array...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2011) 138 (17): 3745–3757.
Published: 1 September 2011
... and cerebellum. Positioning of the mid-hindbrain boundary (MHB) within the neuroepithelium is dependent on the interface of Otx2 and Gbx2 expression domains, yet in the absence of either or both of these genes, organiser genes are still expressed, suggesting that other, as yet unknown mechanisms are also...
Includes: Supplementary data
Journal Articles
Andrea L. Zamparini, Tim Watts, Clare E. Gardner, Simon R. Tomlinson, Geoffrey I. Johnston, Joshua M. Brickman
Journal:
Development
Development (2006) 133 (18): 3709–3722.
Published: 15 September 2006
... that feedback upon these pathways. The homeodomain protein Hex, an early marker of anterior positional information, acts as a transcriptional repressor, suppressing induction and propagation of the Spemman organiser while specifying anterior identity. We show that Hex promotes anterior identity by amplifying...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2003) 130 (21): 5091–5101.
Published: 1 November 2003
... suggest patterning roles for anterior visceral endoderm (AVE) and ADE. Based on similarity of gene expression patterns, fate and a dual role in`protecting' the prospective forebrain from caudalising influences of the organiser, the chick hypoblast has been suggested to be the homologue of the mouse...
Journal Articles
Journal:
Development
Development (2002) 129 (23): 5389–5398.
Published: 1 December 2002
...Carol Irving; Amar Malhas; Sarah Guthrie; Ivor Mason Formation of the trochlear nerve within the anterior hindbrain provides a model system to study a simple axonal projection within the vertebrate central nervous system. We show that trochlear motor neurons are born within the isthmic organiser...
Journal Articles
Journal:
Development
Development (2002) 129 (20): 4785–4796.
Published: 15 October 2002
... 7 2002 © 2002. 2002 Hensen’s node Lateral floor plate Medial floor plate Notochord Organiser Quail/chick chimera CSox1 HNF3β Nkx2.2 Shh When Hensen’s node is replaced in 5-6 ss chick embryo by its quail counterpart ( Fig. 2 E, red), floor-plate and notochord...
Journal Articles
Journal:
Development
Development (2000) 127 (11): 2303–2315.
Published: 1 June 2000
... by the down-regulation of Goosecoid and Chordin , while induction of dorsal mesoderm by Hex-λVP2 results in activation of these genes. Transient transfection experiments in ES cells suggest that Goosecoid is a direct target of Hex. Together, our results support a model in which Hex suppresses organiser...
Journal Articles
Journal:
Development
Development (1998) 125 (13): 2371–2380.
Published: 1 July 1998
... contributed equally to this work † Present address: NIH, NICHHD, Blg 6B, Rm 4B/420, 9000 Rockville Pike, Bethesda, MD, 20892-2790, USA 03 06 1998 20 04 1998 © 1998 by Company of Biologists 1998 Mix.1 Xenopus Endoderm Mesoderm Siamois Organiser Head...
Journal Articles
Journal:
Development
Development (1997) 124 (21): 4275–4286.
Published: 1 November 1997
... mesendoderm which lacks dorsalising activity, can only be activated by the VCC/ Siamois pathway in vegetal cells. We propose that the regionalisation of the organiser during gastrulation proceeds from the differential interpretation along the animal-vegetal axis of the activation of the VCCβ-catenin/ Siamois...
Journal Articles
Journal:
Development
Development (1992) 114 (2): 403–415.
Published: 1 February 1992
... notochord mesoderm cell commitment Dil organiser During embryonic development, cells become committed to their fates gradually, through a hierarchy of developmental decisions until they finally differentiate - that is, they acquire the morphological and biochemical characteristics...
Journal Articles
Journal:
Development
Development (1989) 107 (2): 229–241.
Published: 1 October 1989
... plan when grafted to the ventral marginal zone of a similarly aged host embryo ( Cooke et al . 1987 ). This replicates the natural control of this phase of development by the dorsal blastoporal lip when similarly grafted; the classical ‘organiser’ phenomenon. I have explored systematically the effect...