...-specific protein family with unknown molecular function controls when cells exit proliferation and changes the final organ size in Arabidopsis . Dwarf Organ size control Proliferation exit Genes of unknown function Arabidopsis thaliana National Science Foundation http://dx.doi.org...

.... Morphogenesis Hydraulic gating Organ size control Synthetic cysts Biological organs are formed via iterations and variations of just a few geometric/topological themes: folding, lumenization and segmentation. The regulation of their size and shape is crucial for normal physiological function...

... the FGF, EGF, Hedgehog, TGFβ, Wnt and Hippo pathways, are now relatively well defined, the mechanisms by which these pathways interact to precisely regulate organ size are still largely unexplored. Fz4 Fz8 Kidney development Wnt11 Wnt signaling Organ size control Mouse © 2011. 2011...

..., whereas tissue lacking fat or expanded is not. Here we explore the relative contribution of SWH pathway proteins to organ size control by determining their temporal activity profile throughout Drosophila melanogaster eye development. We show that eye tissue lacking fat, expanded or discs overgrown...