... and spatial expression of Zscan4 is fine-tuned at the oocyte-to-embryo transition. Thus, the H3.3 chaperone Hira complex has a maternal effect function in oocyte developmental competence and embryogenesis, through modulating chromatin condensation and transcriptional quiescence. References Ahmed , K...

....   62 . 10.4081/ejh.2018.2972 Lu , X. , Gao , Z. , Qin , D. and Li , L. ( 2017 ). A maternal functional module in the mammalian oocyte-to-embryo transition . Trends Mol. Med.   23 , 1014 - 1023 . 10.1016/j.molmed.2017.09.004 Mahadevan , S. , Sathappan , V...

... that proteasomes are present in a gradient with the highest levels in the animal hemisphere and extending into the vegetal hemisphere of Xenopus oocytes. This distribution changes dramatically during the oocyte-to-embryo transition, with proteasomes becoming enriched in and restricted to the animal hemisphere...

... to fertilization are essential for mediating the oocyte-to-embryo transition. Here, we describe a comprehensive small-molecule screen focused on identifying compounds that affect early embryonic events in Caenorhabditis elegans . We identify a single novel compound that disrupts early embryogenesis with remarkable...

... Germline Oocyte-to-embryo transition MBK-2 Primordial germ cells, the source of gametes in the adult animal and the genetic link between two generations, are specified early during embryogenesis in most animals. Recent studies in worms, flies and mice show that specification of primordial...