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Keywords: Oocyte polarity
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Journal Articles
Journal: Development
Development (2014) 141 (4): 842–854.
Published: 15 February 2014
... in zebrafish as a novel vertebrate-specific regulator of oocyte polarity, acting through unknown molecular interactions. Here we show that endogenous Buc protein localizes to the Balbiani body, a conserved, asymmetric structure in oocytes that requires Buc for its formation. Asymmetric distribution of Buc...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (10): 1991–2001.
Published: 15 May 2011
...Yi Sun; Yan Yan; Natalie Denef; Trudi Schüpbach The Drosophila body axes are established in the oocyte during oogenesis. Oocyte polarization is initiated by Gurken, which signals from the germline through the epidermal growth factor receptor (Egfr) to the posterior follicle cells (PFCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (9): 1697–1703.
Published: 01 May 2011
... in the posterior follicle cells lead to oocyte polarization defects similar to those caused by mutations in the Hippo signaling pathway. PI4KIIIalpha mutations also cause misexpression of well-established Hippo signaling targets. The Merlin-Expanded-Kibra complex is required at the apical membrane for Hippo...
Journal Articles
Journal: Development
Development (2008) 135 (3): 463–471.
Published: 01 February 2008
... to the oocyte posterior, thereby dividing the cortex into different domains along the AP axis. Active Lgl promotes the formation of actin-rich projections at the oocyte cortex and the posterior enrichment of the serine/threonine kinase Par-1, a key step for oocyte polarization. Our studies suggest that Lgl...
Includes: Supplementary data