... nurse cells. (E,F) Ovarioles from wild-type (E) and mio2 homozygous female (F). Ovarioles were stained with Hoechst to visualize nuclei. O, oocyte. Oocyte differentiation, as well as the maintenance of the meiotic cycle,are dependent on the microtubule-based directional transport of specific mRNAs...

..., 1997 ). Studies over the last few years suggest that oocyte differentiation is a two-step process. The first step entails the establishment of an asymmetry between the pro-oocyte and the pro-nurse cells. Exactly when and how this asymmetry is established is unknown, although it may occur as early...

... in the germarium of Drosophila melanogaster . J. Cell Biol . 45 , 306 – 320 . 10.1083/jcb.45.2.306 McGrail , M. and Hays , T. S. ( 1997 ). The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila...

... of Biologists 1996 Drosophila oogenesis nurse cell differentiation oocyte differentiation Stonewall transcription factor Cells are the targets for a broad range of both extrinsic and intrinsic differentiation factors. Molecular pairs of diffusible ligands and membrane bound receptors...