... of embryonic ventral body wall closure in amniotes. Omphalocele Fibroblast growth factor Ventral body wall Other signaling pathways have been implicated in controlling VW morphogenesis including the Hedgehog ( Matsumaru et al., 2014 ), TGFβ ( Aldeiri et al., 2017 ), PCP ( Murdoch et al., 2014...

... pathway in the lung development in mice, we performed tissue-specific deletions of Mek1 function on a Mek2 null background. Inactivation of both Mek genes in mesenchyme resulted in several phenotypes, including giant omphalocele, kyphosis, pulmonary hypoplasia, defective tracheal cartilage and death...