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Keywords: Obesity
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Journal Articles
Journal: Development
Development (2016) 143 (6): 950–961.
Published: 15 March 2016
... and the postnatal development of obesity has been established. Here, by comparing adipocytes differentiated from mesenchymal stem cells (MSCs) taken from the umbilical cord and derived from normal and growth-restricted neonates, we identified the transcription factor SOX6 as highly expressed only in growth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (4): 681–691.
Published: 15 February 2015
..., the temporal and mechanistic origins of these changes, and whether they are reversible, are unknown. We now show that, in obese female mice, cumulus-oocyte complexes exhibit endoplasmic reticulum (ER) stress, high levels of intracellular lipid, spindle abnormalities and reduced PTX3 extracellular matrix...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4731–4735.
Published: 1 December 2006
... and adulthood. We speculate that this mechanism could be important in explaining the well-established link between obesity and insulin resistance that is observed in Type 2 diabetes. * Author for correspondence (e-mail: clive.wilson@anat.ox.ac.uk ) 25 9 2006 © 2006. 2006 Drosophila...
Includes: Supplementary data