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Keywords: O-fucosyltransferase
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Journal Articles
Takeshi Sasamura, Hiroyuki O. Ishikawa, Nobuo Sasaki, Syunsuke Higashi, Maiko Kanai, Shiho Nakao, Tomonori Ayukawa, Toshiro Aigaki, Katsuhisa Noda, Eiji Miyoshi, Naoyuki Taniguchi, Kenji Matsuno
Journal:
Development
Development (2007) 134 (7): 1347–1356.
Published: 1 April 2007
... the plasma membrane to the early endosome, which we show was independent of the O -fucosyltransferase activity of O-fut1. We also found that O-fut1 promoted the turnover of Notch, which consequently downregulated Notch signaling. O-fut1 formed a stable complex with the extracellular domain of Notch...
Journal Articles
An O -fucose site in the ligand binding domain inhibits Notch activation
Available to Purchase
Journal:
Development
Development (2003) 130 (26): 6411–6421.
Published: 29 December 2003
... to Notch overexpression in the wing. fringe Notch Fucose Glycosylation O-fucosyltransferase Drosophila The Notch pathway is a signal transduction pathway that plays key roles in regulating cell fate decisions throughout metazoan development( Artavanis-Tsakonas et al.,1999...
Journal Articles
neurotic , a novel maternal neurogenic gene, encodes an O -fucosyltransferase that is essential for Notch-Delta interactions
Available to PurchaseTakeshi Sasamura, Nobuo Sasaki, Fumiyasu Miyashita, Shiho Nakao, Hiroyuki O. Ishikawa, Mikiko Ito, Motoo Kitagawa, Kenichi Harigaya, Eric Spana, David Bilder, Norbert Perrimon, Kenji Matsuno
Journal:
Development
Development (2003) 130 (20): 4785–4795.
Published: 15 October 2003
... of mammalian GDP-fucose protein O -fucosyltransferase, which adds fucose sugar to epidermal growth factor-like repeats and is known to play a crucial role in Notch signalling. neurotic functions in a cell-autonomous manner, and genetic epistasis tests reveal that Neurotic is required for the activity...
