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Keywords: Nuclear migrationClose
Development (2023) 150 (19): dev202115.
Published: 11 October 2023
...Jamie Ho; Leslie A. Guerrero; Diana E. Libuda; G. W. Gant Luxton; Daniel A. Starr ABSTRACT Successful nuclear migration through constricted spaces between cells or in the extracellular matrix relies on the ability of the nucleus to deform. Little is known about how this takes place in vivo . We...
Includes: Supplementary data
Development (2016) 143 (22): 4193–4202.
Published: 15 November 2016
... deformation. Here, we establish an in vivo model in which nuclei can be visualized while moving through constrictions and use it to elucidate mechanisms for nuclear migration. C. elegans hypodermal P-cell larval nuclei traverse a narrow space that is about 5% their width. This constriction is blocked...
Includes: Supplementary data
Development (2009) 136 (16): 2725–2733.
Published: 15 August 2009
...Marina Meyerzon; Heidi N. Fridolfsson; Nina Ly; Francis J. McNally; Daniel A. Starr Intracellular nuclear migration is essential for many cellular events including fertilization, establishment of polarity, division and differentiation. How nuclei migrate is not understood at the molecular level...
Development (2004) 131 (19): 4677–4686.
Published: 1 October 2004
... of photoreceptor nuclear position depends on a balance of plus-end and minus-end directed microtubule motor function. © 2004. 2004 Nuclear migration Dynein Capping protein Dynamitin Kinesin Neurons are highly polarized cells whose cell bodies extend processes specialized for receiving...
Daniel A. Starr, Greg J. Hermann, Christian J. Malone, William Fixsen, James R. Priess, H. Robert Horvitz, Min Han
Development (2001) 128 (24): 5039–5050.
Published: 15 December 2001
...Daniel A. Starr; Greg J. Hermann; Christian J. Malone; William Fixsen; James R. Priess; H. Robert Horvitz; Min Han Nuclear migration plays an essential role in the growth and development of a wide variety of eukaryotes. Mutations in unc-84, which encodes a conserved component of the nuclear...
Development (2000) 127 (4): 841–850.
Published: 15 February 2000
... Oogenesis TGFβ EGF Nuclear migration Follicle cell patterning Broad Complex kekkon pipe Pathway synergy The anterior-posterior (AP) and dorsal-ventral axes (DV) of the Drosophila egg and embryo are established during oogenesis by two consecutive steps of cell signaling from...
Development (1999) 126 (14): 3171–3181.
Published: 15 July 1999
...Christian J. Malone; William D. Fixsen; H. Robert Horvitz; Min Han ABSTRACT Nuclear migrations are essential for metazoan development. Two nuclear migrations that occur during C. elegans development require the function of the unc-84 gene. unc-84 mutants are also defective in the anchoring...
Development (1999) 126 (5): 927–934.
Published: 1 March 1999
... embryonic axis. * Author for correspondence (e-mail: Karess@cgm.cnrs-gif.fr ) 14 12 1999 © 1999 by Company of Biologists 1999 Broad-Complex Axis specification Nuclear migration Follicle cell Patterning gurken signaling Patterning in the developing Drosophila...
Development (1997) 124 (8): 1497–1507.
Published: 15 April 1997
..., and a general deficit and disorder of retinal cells. We have characterized the developmental phenotype in Glued 1 and found defects in multiple stages of eye development, including mitosis, nuclear migration, cell fate determination, rhabdomere morphogenesis and cell death. Transgenic flies that express...
Development (1994) 120 (9): 2609–2618.
Published: 1 September 1994
... and cell bodies rise apically and then settle into position in the cell group. The final nuclear positions determine the shape of the individual cells. We have identified a Drosophila gene called marbles which is required for the apical nuclear migrations that accompany cell determination during eye...
Development (1991) 111 (4): 909–920.
Published: 1 April 1991
..., the mutants exhibited retarded nuclear migration while synchronous nuclear divisions were unaffected. The retarded migration causes nuclei to remain in the anterior part of the embryo retaining their spherical distribution even in a late cleavage stage. This consequently results in an extreme delay in nuclear...