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Keywords: Notum
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Journal Articles
Journal: Development
Development (2015) 142 (24): 4217–4229.
Published: 15 December 2015
... brain cell number through epimorphosis or decreasing brain cell number through tissue remodeling (morphallaxis), as appropriate. We identified a pathway controlling a brain size set-point that involves feedback inhibition between wnt11-6/wntA/wnt4a and notum , encoding conserved antagonistic signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2416–2425.
Published: 1 July 2012
... with Wnts, these glycosophosphotidylinositol (GPI)-anchored, heparan-sulfate proteoglycans bind ligands of several other signaling pathways in both vertebrates and invertebrates. In Drosophila , Notum, a secreted α/β-hydrolase, antagonizes the signaling of the prototypical Wnt Wingless (Wg), by releasing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (18): 4087–4096.
Published: 15 September 2005
... of a boundary that does not rely on such restrictions, namely, that which separates the notum (body wall) and the wing hinge (appendage). It is known that the homeobox genes of the Iroquois complex (Iro-C) define the notum territory and that the distal limit of the Iro-C expression domain demarks the boundary...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4931–4941.
Published: 15 October 2003
... cells maintain a spatial relationship even after the separation of their lineages. The peripodial membrane plays a significant role during the regional subdivision of the wing disc into presumptive wing, notum and hinge. The Egfr/Ras pathway mediates this function of the peripodial membrane...