... epithelial migration driven by pulsatile actomyosin contractility. Palate Collective cell migration Apoptosis Cell extrusion Tgfβ Cleft palate Cleft lip Craniofacial Live imaging Fusion Actomyosin Cell adhesion Non-muscle myosin II NMIIA Mouse National Institute of Dental...

... the formation of the dense circumferential actomyosin belt. Strikingly, Lmo7 binds non-muscle myosin II (NMII) and recruits it to apical junctions and the apical cortex. This NMII recruitment is essential for Lmo7-mediated apical constriction. Lmo7 knockdown decreases NMIIA localization at apical junctions...

... protein cofilin 1. Atp2c1 Neural tube closure Apical constriction Ca 2+ Cofilin 1 Non-muscle myosin II Mouse The mammalian brain and spinal cord develop from the neural tube, an embryonic structure that starts out as a flat epithelial sheet and undergoes extensive morphogenetic...

.... Moreover, we show by pharmacological and genetic studies that non-muscle myosin II is a key regulator of this distribution of basal bodies. This study demonstrates that the orientation and distribution of basal bodies occur by distinct mechanisms. * Author for correspondence ( [email protected]...

.... © 2009. 2009 Actin Non-muscle myosin II Morphogenesis Phosphorylation Rho kinase C. elegans Morphogenesis is an essential feature of embryonic development, during which cells change their overall shape to build tubular organs, extend cell sheets or organize into specific...