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Keywords: Nkx2.1
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Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (8): 1559–1567.
Published: 15 April 2008
...Tonggong Du; Qing Xu; Polloneal J. Ocbina; Stewart A. Anderson In the ventral telencephalon, the medial ganglionic eminence (MGE) is a major source of cortical interneurons. Expression of the transcription factor NKX2.1 in the MGE is required for the specification of two major subgroups of cortical...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (15): 2815–2827.
Published: 1 August 2007
... criteria and expression patterns of Darpp-32, Tbr1, Nkx2.1 and Pax6 genes, we show in slice cultures of turtle embryos that early cohorts of tangentially migrating cells are released from the medial ganglionic eminence between stages 14 and 18. Additional populations migrate tangentially from the dorsal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (13): 2521–2531.
Published: 1 July 2007
...Jianwen Que; Tadashi Okubo; James R. Goldenring; Ki-Taek Nam; Reiko Kurotani; Edward E. Morrisey; Olena Taranova; Larysa H. Pevny; Brigid L. M. Hogan Sox2 is expressed in developing foregut endoderm, with highest levels in the future esophagus and anterior stomach. By contrast, Nkx2.1 (Titf1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (22): 4987–4998.
Published: 15 November 2005
... harboring conditional mutations in Shh within the neural tube. At embryonic day 12.5, NestinCre: Shh Fl/Fl mutants have a relatively normal index of S-phase cells in the MGE, but many of these cells do not co-express the interneuron fate-determining gene Nkx2.1. This effect is reproduced by inhibiting Shh...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (1): 35–47.
Published: 1 January 2005
... of a pulmonary cell fate using embryo tissue explants. We show that NKX2.1, an early transcription factor crucial for lung development, is expressed in the ventral foregut endoderm shortly after albumin and Pdx1, early markers of the liver and pancreas lineages, respectively. Similar to hepatic specification...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4895–4906.
Published: 15 October 2003
...Joshua G. Corbin; Michael Rutlin; Nicholas Gaiano; Gord Fishell Regional patterning of the mammalian telencephalon requires the function of three homeodomain-containing transcription factors, Pax6, Gsh2 and Nkx2.1. These factors are required for the development of the dorsal, lateral and medial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (7): 1225–1234.
Published: 1 April 2003
... induced ectopic bud formation in the esophagus by activating the expression of Fgf10 . Conversely,interference of Tbx4 function resulted in repression of Fgf10 expression and in failure of lung bud formation. In addition, ectopic Tbx4 or Fgf10 also induced ectopic expression of Nkx2.1 , a marker gene...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3751–3760.
Published: 1 August 2002
... (e-mail: klaus.rohr@uni-koeln.de ) 30 4 2002 © 2002. 2002 Hypothyroidism Thyroid Pax2 Pax8 Nkx2.1 TTF1 Evolution Zebrafish Mouse The thyroid gland is responsible for producing thyroid hormone in all vertebrates. Although thyroid hormone is best known...
Journal Articles
Journal Articles