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Maria Serra, Konstantinos-Dionysios Alysandratos, Finn Hawkins, Katherine B. McCauley, Anjali Jacob, Jinyoung Choi, Ignacio S. Caballero, Marall Vedaie, Anita A. Kurmann, Laertis Ikonomou, Anthony N. Hollenberg, John M. Shannon, Darrell N. Kotton
Development (2017) 144 (21): 3879–3893.
Published: 1 November 2017
..., as these two cell types each originate from Nkx2-1 + foregut progenitors and the minimal pathways claimed to regulate their distinct lineage specification in vivo or in vitro have varied in previous reports. Here, we employ PSCs to identify the key minimal signaling pathways (Wnt+BMP versus BMP+FGF...
Includes: Supplementary data
Development (2002) 129 (3): 761–773.
Published: 1 February 2002
... Nkx2-1 , a homeobox gene whose expression is restricted to two domains within the forebrain: the basal telencephalon and the hypothalamus. Molecular respecification of the basal telencephalon and hypothalamus in Nkx2-1 -deficient mice causes a severe defect in the guidance of layer 5 cortical...