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Keywords: Neurotrophins
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (16): dev200583.
Published: 19 August 2022
... and pain transduction. Pea3 NGF Neurotrophins Sensory neurons Noxious pain Peripheral innervation Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT-2017-4597 PICT-2019-1467 PICT-2019-1472 PICT-2017-4513 Consejo Nacional de...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (20): dev181750.
Published: 24 October 2019
... and neurotrophin 3 signaling are necessary for maintenance of RUNX3 expression in PSNs. Hence, a transcriptional regulator that is crucial for specifying a generic PSN type identity after neurogenesis is later regulated by target muscle-derived signals to contribute to the specialized aspects of the sensorimotor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (7): 1407–1417.
Published: 1 April 2007
..., activation of the P2X receptor signaling pathway by ATPγS or α,βMeATP inhibited BDNF-induced neurite outgrowth and branching. These findings indicate that P2X receptor signaling provides a mechanism for inhibiting neurotrophin support of SGN neurites when synaptic reorganization is occurring in the cochlea...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (13): 3147–3160.
Published: 1 July 2002
... zone; VZ: ventricular zone; DG: developing dentate gyrus; pCA: putative CA regions; VI: cortical layer VI. Scale bars: 150 μm in C-E; 30 μm in F,G; 250 μm in H; 350 μm in I-K; 300 μm in L; 75 μm in M,N; 200 μm in O. Neurotrophin stimulation of the TrkB receptor leads to activation of the MAP...
Journal Articles
Journal: Development
Development (2001) 128 (19): 3685–3695.
Published: 1 October 2001
... of development. *Author for correspondence (e-mail: alun.davies@ed.ac.uk ) 2 7 2001 © 2001. 2001 Artemin Sympathetic neurones Mouse Neurotrophins Artemin ( Baloh et al., 1998 ) is the most recently identified member of the glial cell line-derived neurotrophic factor (GDNF...
Journal Articles
Journal Articles
Journal: Development
Development (2000) 127 (9): 1943–1951.
Published: 1 May 2000
... of genetic determination implicates environmental factors in this selection and specification process. We analysed, in organotypic visual cortex cultures, the specification of neurons expressing neuropeptide Y (NPY), a potent anticonvulsant. Endogenous brain-derived neurotrophic factor and neurotrophin 4/5...
Journal Articles
Journal: Development
Development (1997) 124 (7): 1333–1342.
Published: 1 April 1997
...-mail: christopher.nosrat@neuro.ki.se ) 18 03 1998 30 01 1998 © 1997 by Company of Biologists 1997 taste buds sensory organ gustatation neurotrophins knockout lingual Taste buds are chemosensory organs consisting of collections of spindle-shaped modified epithelial cells...
Journal Articles
Journal: Development
Development (1996) 122 (2): 715–724.
Published: 1 February 1996
...S. E. McKay; A. Garner; J. Caldero; R. P. Tucker; T. Large; R. W. Oppenheim ABSTRACT The neurotrophin, brain-derived neurotrophic factor, prevents motoneuron cell death during the normal development of the chick embryo. Brain-derived neurotrophic factor is a ligand for the low-affinity NGF receptor...
Journal Articles
Journal: Development
Development (1996) 122 (1): 301–307.
Published: 1 January 1996
...Michaela Ockel; Gary R. Lewin; Yves-Alain Barde ABSTRACT The neurotrophins nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 are structurally related proteins regulating the number of neurons in peripheral ganglia of the nervous system. Increased levels of nerve growth...
Journal Articles
Journal Articles
Journal: Development
Development (1995) 121 (8): 2461–2470.
Published: 1 August 1995
... diffusion is much less extensive than that of NGF ( Yan et al., 1994 ). Regulation of neurotrophin availability by differential expression of truncated receptors may not be limited to BDNF: truncated forms of the NT-3 receptor trkC are present both in mammals ( Valenzuela et al., 1993 ) and in chick...
Journal Articles
Journal: Development
Development (1995) 121 (5): 1301–1309.
Published: 1 May 1995
... in vivo: cerebellar neurites generally extended only on spinal cord, sympathetic neurites on sciatic nerve, and DRG neurites on both. Neurite growth from DRG neurons has been shown to be stimulated by neurotrophins. To determine whether neurotrophins might also affect the substrate preferences of neurites...
Journal Articles
Journal: Development
Development (1994) 120 (6): 1643–1649.
Published: 1 June 1994
... expression of the BDNF gene might be important in the co-ordinated development of the visual system. * Author for correspondence 16 03 1994 © 1994 by Company of Biologists 1994 neurogenesis neurotrophins optic tectum retina mRNA quantification Neurons require signals...
Journal Articles
Journal Articles
Journal: Development
Development (1994) 120 (6): 1613–1619.
Published: 1 June 1994
...Franziska Gaese; Roland Kolbeck; Yves-Alain Barde ABSTRACT The role played by neurotrophin-3 during the development of quail sensory ganglia was investigated using a mono-clonal antibody that specifically blocks the biological activity of this neurotrophin. Neutralisation of neu-rotrophin-3...
Journal Articles
Journal: Development
Development (1994) 120 (4): 1027–1033.
Published: 1 April 1994
...Kuo-Fen Lee; Alun M. Davies; Rudolf Jaenisch ABSTRACT To understand the role of low-affinity neurotrophin receptor p75 in neural development, we previously generated mice carrying a null mutation in the p75 locus (Lee, K. F., Li, E., Huber, L. J., Landis, S. C., Sharpe, A. H., Chao, M. V...
Journal Articles