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Keywords: Neurons
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Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (8): dev200425.
Published: 3 May 2022
... of the brain. Apart from being highly specialized brain phagocytes, microglia modulate the development and functions of neurons and glial cells through both direct and indirect interactions. Thus, recognizing the elements that influence the homeostasis and heterogeneity of microglia in normal brain development...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (14): dev176735.
Published: 22 July 2019
... from proliferating progenitors to differentiated neurons. Functional experiments demonstrated the pivotal role of Yap/Taz-TEAD signaling in maintaining progenitor features in the hindbrain boundary cell population. * Present address: ZeClinics, 08003 Barcelona, Spain. ‡ Author...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 1983–1986.
Published: 15 May 2014
...Simon M. G. Braun; Sebastian Jessberger New neurons are generated throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, has been implicated in physiological brain function, and failing or altered neurogenesis has been associated with a number...
Journal Articles
Journal: Development
Development (2013) 140 (2): 323–332.
Published: 15 January 2013
... has been made by studying the zebrafish parapineal organ, a group of neurons on the left side of the epithalamus. Parapineal cells arise from the medially located pineal complex anlage and migrate to the left side of the brain. We have found that Fgf8a regulates a fate decision among anterior pineal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3392–3401.
Published: 15 September 2012
... Receptor (EcR-B1) expression in MB neurons. This is phenocopied in CORL-RNAi and Smad2-RNAi clones in wild-type larvae. Furthermore, constitutively active Baboon (type I receptor upstream of Smad2) cannot stimulate EcR-B1 MB expression in Df(4)dCORL larvae, which demonstrates a formal requirement for CORL...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (17): 2885–2894.
Published: 1 September 2010
... pathway in clones of cells to study their effects on nerve pathfinding within the peripheral nervous system. We find that high levels of Engrailed make the epidermal cells inhospitable to bristle neurons; sensory axons that are too near these cells are either deflected or fail to extend properly or at all...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2583–2592.
Published: 1 August 2008
... in neuronal function in postmitotic,differentiated neurons. Here, we demonstrate a novel role for the canonical Notch signalling pathway in postmitotic neurons during a specialised`diapause-like' post-embryonic developmental stage in C. elegans called dauer. Our data suggest that cell signalling downstream...
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (8): 1951–1959.
Published: 15 April 2005
... ( Fig. 3A ). Subsets of GFP-labelled neurons in the lateral cord co-expressed Lbx1, which marks early postmitotic neurons derived from dP4, dP5 and dP6( Muller et al., 2002 )( Fig. 3D ). Other GFP-labelled neurons in the ventral spinal cord expressed Evx1, which marks neurons derived from the p0 domain...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3717–3726.
Published: 1 August 2004
...-mediated gene transfer in cortical organotypic slice cultures established from early postnatal mice to study the effects of HGF on the development of dendritic arbors of pyramidal neurons. Compared with untreated control cultures, exogenous HGF promoted a highly significant increase in dendritic growth...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4553–4566.
Published: 1 October 2003
... be stimulated by expression of activated EGL-30 in neurons, or by an EGL-30-dependent change in behavior that occurs in a liquid environment. Our results indicate that excitable cells and animal behavior can provide modulatory inputs into the effects of growth factor signaling on cell fates,and suggest...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2187–2198.
Published: 15 May 2003
.... These analyses demonstrate that glial cell line-derived neurotrophic factor (GDNF) and neurturin are important for different aspects of ENS development. Neurturin is essential for maintaining the size of mature enteric neurons and the extent of neuronal projections, but does not influence enteric neuron number...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 118 (2): 539–552.
Published: 1 June 1993
...-A and PDGF-B), and the alpha and beta subunits of the PDGF receptor (PDGFR αR and PDGF βR). We have also visualized PDGF-A protein in these tissues by immunohistochemistry. In the retina, PDGF-A mRNA is present in pigment epithelial cells, ganglion neurons and a subset of amacrine neurons. PDGF-A transcripts...
Journal Articles
Journal: Development
Development (1993) 117 (2): 689–700.
Published: 1 February 1993
...Kathryn Edson; Brigitte Weisshaar; Andrew Matus ABSTRACT We have previously shown that microtubules in non-neuronal cells form long, stable bundles after transfection with the embryonic neuronal microtubule-associated protein MAP2c. In this study, we found that treating MAP2c-transfected cells...
Journal Articles
Journal: Development
Development (1992) 116 (4): 1151–1161.
Published: 1 December 1992
...Brigitte Weisshaar; Thierry Doll; Andrew Matus ABSTRACT Microtubule-associated protein 2c (MAP2c) is one of a set of embryonic MAP forms that are expressed during neuronal differentiation in the developing nervous system. We have investigated its mode of action by expressing recombinant protein...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 114 (1): 17–29.
Published: 1 January 1992
...F. Lafont; M. Rouget; A. Triller; A. Prochiantz; A. Rousselet ABSTRACT We have studied the effects of proteoglycans (PGs) and glycosaminoglycans (GAGs) on the growth and morphology of neurons in culture. PGs from glial cells or Engelbreth-Hohn-Swarm tumor cells (EUS), pure bovine kidney heparan...