... is a specific marker for bipotent neuronal progenitors, expressed in cycling interstitial cells that give rise to apical neurons and gastric nematoblasts (i.e. sensory mechanoreceptor precursors). cnox-2 RNAi silencing leads to a dramatic downregulation of hyZic, prdl-a, gsc and cnASH , whereas hyCOUP-TF...

... on the division of neuronal progenitors, which can lead to cell cycle exit in vivo and restricts the proliferation rate in vitro. Interestingly, this effect was observed both in concert with and independently of neuronal differentiation. As estimated by BrdU incorporation, GATA2 expression can...