... with the currently circulating Asian lineage of ZIKV (MEX1-44), DENV2 grows slower, causes less neuronal death and fails to cause postnatal animal death. Surprisingly, our side-by-side comparison uncovered that the African ZIKV isolate (MR-766) is more potent at causing brain damage and postnatal lethality than MEX1...

... neuronal death During the development of the nervous system, the final number of nerve cells in any one adult structure represents the combined effects of additive processes such as cell division and subtractive processes such as cell death. Cell division typically occurs in the ventricular...

... 19 08 1993 © 1993 by Company of Biologists 1993 neuronal development hormonal regulation neurobiology ecdysteroid 20-hydroxyecdysone neuronal death Steroid hormones, thyroid hormones and retinoids are involved in the coordination of complex developmental processes...

... is most marked during the period of natural neuronal death in vivo , suggesting that TMN neurones are most sensitive to the neurotrophic effects of SMx and BDNF at the same time as their survival is critically dependent on forming appropriate peripheral and central connections. Developing sensory...