... ( Haidet-Phillips et al., 2011 ; Jo et al., 2014 ; Messing et al., 2012 ; Molofsky et al., 2012 ; Orre et al., 2014 ). Human astrocyte development Astrocyte heterogeneity RNA-seq Neuron-glia interaction Blood-brain barrier Summary: Astrocytes generated from hPSC-derived regional...

... during Drosophila eye development. Fizzy/Cdc20 controls the early growth of the eye disc anlage and the concomitant entry of glial cells onto the disc. In contrast, fzr/cdh1 acts during neuronal patterning and photoreceptor axon growth, and subsequently affects neuron-glia interaction. To further address...

...: Differentiation of Drosophila wrapping glia affects axonal wrapping and blood-brain barrier development through autocrine activation of the EGF receptor, similar to mammalian re-myelination after injury. Drosophila Wrapping glia Neuregulin Subperineurial glia Septate junction Neuron-glia...

... that mediate the recognition and specific adhesion of glial and axonal membranes are largely unknown. We use the Drosophila midline of the embryonic central nervous system as a model to investigate these neuron glia interactions. During development, the midline glial cells acquire close contact to commissural...

..., FRG astrocytes blood-brain barrier developmental regulation ELISA glycosylation integral membrane protein in vitro culture neuron-glia interaction neurothelin two-dimensional gel electrophoresis. The blood-brain barrier represents a complex system of active and passive...