... confer anteroposterior pattern to the embryo. We have analysed the progenitor population transcriptomes in the mouse primitive streak and tail bud throughout axial elongation. Transcriptomic signatures distinguish three known progenitor types (neuromesodermal, lateral/paraxial mesoderm and notochord...

... by The Company of Biologists Ltd 2015 Summary: In response to high levels of Wnt, tbx16 irreversibly flips a bistable switch that allows maintenance of mesodermal fate while repressing the bipotential neuromesodermal progenitor state in zebrafish embryos. Bipotential Neuromesodermal Wnt...