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Keywords: Neurog2
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Journal Articles
Michael L. Kaufman, Noah B. Goodson, Ko Uoon Park, Michael Schwanke, Emma Office, Sophia R. Schneider, Joy Abraham, Austin Hensley, Kenneth L. Jones, Joseph A. Brzezinski
Journal:
Development
Development (2021) 148 (12): dev199399.
Published: 18 June 2021
... RNA-sequencing of nascent Otx2 + cells identified the bHLH factors Ascl1 and Neurog2 as candidate regulators. CRISPR/Cas9 targeting of these factors showed that only the simultaneous loss of Ascl1 and Neurog2 prevented OTX2 expression. Our findings suggest that Ascl1 and Neurog2 act either redundantly...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2017) 144 (20): 3674–3685.
Published: 15 October 2017
...Hao Lin; Xuechen Zhu; Geng Chen; Lei Song; Li Gao; Aftab A. Khand; Ying Chen; Gufa Lin; Qinghua Tao Neurog2 is a crucial regulator of neuronal fate specification and differentiation in vivo and in vitro . However, it remains unclear how Neurog2 transactivates neuronal genes that are silenced...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2014) 141 (16): 3243–3254.
Published: 15 August 2014
...Kate A. Maurer; Amy N. Riesenberg; Nadean L. Brown Notch signaling regulates basic helix-loop-helix (bHLH) factors as an evolutionarily conserved module, but the tissue-specific mechanisms are incompletely elucidated. In the mouse retina, bHLH genes Atoh7 and Neurog2 have distinct functions...
Includes: Supplementary data
Journal Articles
Marta Florio, Ketty Leto, Luca Muzio, Andrea Tinterri, Aurora Badaloni, Laura Croci, Paola Zordan, Valeria Barili, Ilaria Albieri, François Guillemot, Ferdinando Rossi, G. Giacomo Consalez
Journal:
Development
Development (2012) 139 (13): 2308–2320.
Published: 1 July 2012
.... During central nervous system development, the proneural gene neurogenin 2 ( Neurog2 ) contributes to many distinct neuronal types by specifying their fate and/or dictating development of their morphological features. By analyzing a mouse knock-in line expressing Cre recombinase under the control...
Includes: Supplementary data
Journal Articles
Amy W. Helms, James Battiste, R. Michael Henke, Yuji Nakada, Nicolas Simplicio, Francois Guillemot, Jane E. Johnson
Journal:
Development
Development (2005) 132 (12): 2709–2719.
Published: 15 June 2005
... Mouse Atoh1 Neurog2 Ascl1 The circuitry of the nervous system depends on complex connections of diverse neuronal cell types. Thus, defining the mechanisms that regulate neuronal diversity is fundamental for understanding how the nervous system functions. Specification of distinct neuronal sub...
Includes: Supplementary data