... abscission during neural differentiation. (A) Drawing of an E4 chick embryo indicating the approximate thoracic level used to generate the transverse sections used in this work. (B) In situ hybridization showing CTNNB1 mRNA distribution in transverse sections of E4 chick SC. (B′,B″) Enlargements...

... the translational landscape during early human neural differentiation and provides insights into the regulation of cell fate determination at the translational level. References Agrawal , M. and Welshhans , K. ( 2021 ). Local translation across neural development: a focus on radial glial cells...

.../ Summary: E2A brings context specificity to the expression of neural genes and the NODAL signaling pathway to control lineage-specific gene expression and cell fate determination during early human development. E2A Neural differentiation Nodal signaling pathway PRC2 complex Human embryonic stem...

... development in vitro and brain development in vivo . These topics were discussed extensively at a recent workshop organized by The Company of Biologists entitled ‘Thinking beyond the dish: taking in vitro neural differentiation to the next level’. Here, we summarize the common themes that emerged from...

... of migration. Taken together, these data suggest that Prdm16 plays an important role in dynamic cellular redox changes in developing neocortex during neural differentiation. * These authors contributed equally to this work ‡ Author for correspondence ( [email protected] ) Competing...

... . 10.1016/j.stem.2013.04.005 Nicoleau , C. , Varela , C. , Bonnefond , C. , Maury , Y. , Bugi , A. , Aubry , L. , Viegas , P. , Bourgois-Rocha , F. , Peschanski , M. and Perrier , A. L. ( 2013 ). Embryonic stem cells neural differentiation qualifies the role...

...Wanqu Zhu; Xiao Yao; Yan Liang; Dan Liang; Lu Song; Naihe Jing; Jinsong Li; Gang Wang Unraveling the mechanisms underlying early neural differentiation of embryonic stem cells (ESCs) is crucial to developing cell-based therapies of neurodegenerative diseases. Neural fate acquisition is proposed...

...Isabel Olivera-Martinez; Nick Schurch; Roman A. Li; Junfang Song; Pamela A. Halley; Raman M. Das; Dave W. Burt; Geoffrey J. Barton; Kate G. Storey Here, we exploit the spatial separation of temporal events of neural differentiation in the elongating chick body axis to provide the first analysis...

... blinded to the experimental conditions. Three to four coverslips in each group were counted. Data are expressed as mean±s.d. Total RNA was extracted from hESCs and neural differentiation cultures using RNA STAT-60 (Tel-Test, Friendswood, TX, USA). cDNA was synthesized using the SuperScript III...

... 26 1 2009 © 2009. 2009 Diencephalon Hypothalamus Dopaminergic neurons Neurosecretory cells otp arnt2 sim1 Neural differentiation Dopaminergic (DA) neurons are involved in control of mood regulation,cognitive function, physiological homeostasis...

... proliferate before they exit from the cell cycle and differentiate into neural cells. However,little is known about the relationship between cell division and neural differentiation, although, in Xenopus , cell division after the onset of gastrulation has been suggested to be nonessential for neural...

... and Wolffe,2000 ). Thus, DNA methylation most probably plays crucial roles in the development and/or function of the CNS( Fan et al., 2001 ; Feng et al., 2005 ). Dnmt1 CpG methylation Neural differentiation STAT1 Chromatin remodeling MeCP2 Histone modification Mouse ©2005. 2005 20...

... zone. Movies and supplemental data available online † Author for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work 28 11 2003 © 2004. 2004 Retina Neural differentiation Axon guidance Target selection Zebrafish...

... resulted in increased proliferation of neural plate cells, causing expansion of the neural field followed by neural tube and craniofacial abnormalities. Overexpressed TH protein repressed neural differentiation and neural crest markers, but did not inhibit the neural inducers, pan-neural markers...

... function is required for neural differentiation of early Xenopus ectoderm. Microinjection of dominant-negative forms of Sox2 ( dnSox2 ) mRNA inhibits neural differentiation of animal caps caused by attenuation of BMP signals. Expression of dnSox2 in developing embryos suppresses expression of N-CAM...

... over spinal motor neurons can be substituted probably by other analysis of the NT3-deficient mice ( Fariñas et al., 1994 ). However, when cultures were treated with N-Shh/VN complexes, neural differentiation raised up to approximately 16% ( Figs 7D , 8D), and the acquisition of the motor neuron...

... the ventral forebrain induction, morphogenesis and evolution. Emx Not1 Pax6 Dlx1 Brain patterning Homeobox Neural differentiation Forebrain Olfactory placode Anterior neural ridge Ganglionic eminence Xenopus ...

... bHLH homeobox Drosophila photoreceptors neural differentiation The Drosophila retina has proven an especially useful model system for examining cell fate induction. It is a simple micro-nervous system consisting of several hundred identical ‘ommatidia’, each of which contains eight...

... Sharpe , C. R. , Fritz , A. , De Robertis , E. M. and Gurdon , J. B. ( 1987 ). A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction . Cell 50 , 749 – 758 . 10.1016/0092-8674(87)90333-3 Sharpe , C...

... tube may be defined by cell position with respect to the ventral midline and controlled by polarizing signals that originate from the floor plate and notochord. Copyright © 1991 by Company of Biologists 1991 dorsoventral patterning floor plate notochord neural differentiation spinal cord...